Kulkarni Kshma, Schow Marie, Shubrook Jay H
J Am Osteopath Assoc. 2020 Feb 1;120(2):107-117. doi: 10.7556/jaoa.2020.020.
In this highly digitalized era, sleep disorders are becoming more common and are associated with an increased burden of chronic disease. Shift workers are at an increased risk for both sleep disorders and metabolic syndrome. In this article, the authors outline the connection between circadian discordance, hormonal imbalance, and the development of metabolic syndrome in shift workers. Based on a literature review of animal model studies, observational studies, and clinical trials conducted between August and October of 2018, the authors offer several clinical interventions, including work schedules, light therapy, medications, and dietary habits to improve the circadian synchronicity of shift workers and reduce their risk of morbidity and mortality. It is important for physicians to be familiar with the consequences of shift work and ways to mitigate the risks for this patient population.
在这个高度数字化的时代，睡眠障碍正变得越来越普遍，并且与慢性病负担的增加相关。轮班工作者患睡眠障碍和代谢综合征的风险更高。在本文中，作者概述了昼夜节律失调、激素失衡与轮班工作者代谢综合征发展之间的联系。基于对2018年8月至10月期间进行的动物模型研究、观察性研究和临床试验的文献综述，作者提供了几种临床干预措施，包括工作时间表、光照疗法、药物治疗和饮食习惯，以改善轮班工作者的昼夜同步性，并降低他们发病和死亡的风险。医生熟悉轮班工作的后果以及减轻该患者群体风险的方法非常重要。
