Graduate Institute of Life Science, National Defense Medical Center, Taipei 11490, Taiwan.
School of Nursing, National Defense Medical Center, Taipei 11490, Taiwan.
Int J Environ Res Public Health. 2021 Sep 17;18(18):9826. doi: 10.3390/ijerph18189826.
Several studies have reported on metabolic syndrome (MetS) based on cross-sectional designs, which cannot show a long-term result. Information is lacking on MetS and related factors based on a longitudinal cohort. This study aimed to examine the relationship between MetS and related factors for a total of six years among hospital employees. A population-based study was conducted, including 746 staff. A total of 680 staff without MetS in 2012 were enrolled in the analysis for repeated measurement of six years of the longitudinal cohort. Data were retrieved from the hospital's Health Management Information System. Analyses were performed using Student's -test, chi-square test, logistic regression, and generalised estimating equations. Statistical significance was defined as < 0.05. Hospital employees aged between 31 and 40 (odds ratio (OR) = 4.596, = 0.009), aged between 41 and 50 (OR = 7.866, = 0.001), aged greater than 50 (OR = 10.312, < 0.001), with a body mass index (BMI) of 25.0~29.9 kg/m (OR = 3.934, < 0.001), a BMI ≥ 30 kg/m (OR = 13.197, < 0.001), higher level of white blood counts (β = 0.177, = 0.001), alanine aminotransferase (β = 0.013, = 0.002), and uric acid (β = 0.223, = 0.005) were at risk of being diagnosed with MetS. The identification of at-risk hospital employees and disease management programs addressing MetS-related factors are of great importance in hospital-based interventions.
一些研究基于横断面设计报告了代谢综合征（MetS），但这些研究无法显示长期结果。基于纵向队列的 MetS 及相关因素的信息缺乏。本研究旨在检查医院员工中 MetS 及相关因素在六年期间的关系。这是一项基于人群的研究，共纳入 746 名员工。2012 年无 MetS 的 680 名员工被纳入分析，以进行六年的纵向队列重复测量。数据从医院的健康管理信息系统中检索。采用 Student's t 检验、卡方检验、逻辑回归和广义估计方程进行分析。统计显著性定义为 < 0.05。医院员工年龄在 3140 岁之间（比值比（OR）=4.596， = 0.009）、4150 岁之间（OR = 7.866， = 0.001）、50 岁以上（OR = 10.312， < 0.001）、体重指数（BMI）在 25.0~29.9 kg/m（OR = 3.934， < 0.001）、BMI ≥ 30 kg/m（OR = 13.197， < 0.001）、较高水平的白细胞计数（β = 0.177， = 0.001）、丙氨酸氨基转移酶（β = 0.013， = 0.002）和尿酸（β = 0.223， = 0.005）的人患 MetS 的风险增加。识别高危医院员工并针对 MetS 相关因素制定疾病管理计划对于医院干预非常重要。
