西班牙因致癌感染导致的癌症死亡负担。
Burden of cancer mortality attributable to carcinogenic infections in Spain.
作者信息
Ferrara Pietro, Agüero Fernando, Masuet-Aumatell Cristina, Ramon-Torrell Josep Maria
机构信息
Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", 5, Via Luciano Armanni, Naples 80138, Italy.
Bellvitge Biomedical Research Institute (IDIBELL), Preventive Medicine Department, University Hospital of Bellvitge, Feixa Llarga s/n, L'Hospitalet de Llobregat 08907, Catalonia, Spain; Clinical Science Department, School of Medicine, University of Barcelona, Feixa Llarga s/n, L'Hospitalet de Llobregat 08907, Catalonia, Spain.
出版信息
Med Clin (Barc). 2020 May 22;154(10):394-397. doi: 10.1016/j.medcli.2019.11.005. Epub 2020 Jan 25.
INTRODUCTION
The impact of carcinogenic infections on cancer-related mortality is unknown.
METHODS
The mortality due to cancers attributable to carcinogenic infections was estimated. The attributable fraction for the infectious agents classified as group 1 carcinogenic in human beings was applied to yearly data on causes of cancer mortality over the period 2013-2017 in Spain according to the International Classification of Diseases (ICD-10).
RESULTS
It was estimated that 9115 deaths (over 110,287 cancer-related deaths, 8.3%) were attributable to infections caused by carcinogenic agents. The estimated number of deaths in men was 5434 (59.6%). The estimated mortality attributable to Helicobacter pylori infection accounted for 48.3% and four agents (H. pylori, HCV, HPV, and HBV) accounted for 96.8% of all cancer deaths attributable to carcinogenic infections. The burden of cancer-related mortality attributable to carcinogenic infections in Spain during the period 2013-2017 was approximately 8%.
CONCLUSIONS
In Spain, one-twelfth of cancer deaths are attributable to carcinogenic infections. Public health measures aiming to reduce the impact of carcinogenic infections are essential.
引言
致癌感染对癌症相关死亡率的影响尚不清楚。
方法
估计致癌感染所致癌症的死亡率。根据国际疾病分类（ICD - 10），将被归类为人类1类致癌物的感染因子的归因分数应用于西班牙2013 - 2017年癌症死亡原因的年度数据。
结果
估计有9115例死亡（在超过110287例癌症相关死亡中占8.3%）可归因于致癌因子引起的感染。男性的估计死亡人数为5434例（占59.6%）。幽门螺杆菌感染所致的估计死亡率占48.3%，四种因子（幽门螺杆菌、丙型肝炎病毒、人乳头瘤病毒和乙型肝炎病毒）占致癌感染所致所有癌症死亡的96.8%。2013 - 2017年期间西班牙致癌感染所致癌症相关死亡率负担约为8%。
结论
在西班牙，十二分之一的癌症死亡可归因于致癌感染。旨在减少致癌感染影响的公共卫生措施至关重要。
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