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猫巨细胞网状核单胺能、肽能及胆碱能传入纤维的起源核团:以霍乱毒素作为逆行示踪剂的双重标记研究

The nuclei of origin of monoaminergic, peptidergic, and cholinergic afferents to the cat nucleus reticularis magnocellularis: a double-labeling study with cholera toxin as a retrograde tracer.

作者信息

Luppi P H, Sakai K, Fort P, Salvert D, Jouvet M

机构信息

Département de Médecine Expérimentale, INSERM U52, CNRS UA 1192, Faculté de Médecine, Lyon, France.

出版信息

J Comp Neurol. 1988 Nov 1;277(1):1-20. doi: 10.1002/cne.902770102.

DOI:10.1002/cne.902770102
PMID:3198792
Abstract

Using a sensitive double-immunostaining technique with nonconjugated cholera toxin B subunit (CT) as a retrograde tracer, we examined the cells of origin and the histochemical nature of afferents to the cat nucleus reticularis magnocellularis (Mc) of the medulla oblongata. After injections of CT confined to the Mc, we found that the major afferents to the Mc arise from: (1) the lateral part of the bed nucleus of the stria terminalis, the nucleus of the anterior commissure, the preoptic area, the central nucleus of the amygdala, the posterior hypothalamus, and the nucleus of the fields of Forel; (2) the Edinger-Westphal nucleus, the mesencephalic reticular formation, and the ventrolateral part of the periaqueductal grey; (3) the nuclei locus coeruleus alpha (LC alpha), peri-LC alpha, locus subcoeruleus, and reticularis pontis oralis and caudalis; (4) the caudal raphe nuclei; and (5) the nucleus reticularis ventralis of the medulla.(ABSTRACT TRUNCATED AT 400 WORDS)

摘要

我们采用一种敏感的双重免疫染色技术,以未结合的霍乱毒素B亚基(CT)作为逆行示踪剂,研究了延髓巨细胞网状核(Mc)传入纤维的起源细胞和组织化学性质。在将CT注射到Mc内后,我们发现Mc的主要传入纤维起源于:(1)终纹床核外侧部、前连合核、视前区、杏仁中央核、下丘脑后部和Forel区核;(2)动眼神经副核、中脑网状结构和导水管周围灰质腹外侧部;(3)蓝斑α核(LCα)、LCα周围核、蓝斑下核以及脑桥嘴侧和尾侧网状核;(4)尾侧中缝核;(5)延髓腹侧网状核。(摘要截于400字)

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