Department of Pharmacy Practice and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, University of Ghana, Legon, Ghana.
Department of Medicine and Therapeutics, University of Ghana Medical School, College of Health Sciences, University of Ghana, Korle-Bu, Ghana.
PLoS One. 2020 Jan 29;15(1):e0227874. doi: 10.1371/journal.pone.0227874. eCollection 2020.
Medication adherence is a key health outcome that reflects the health and general well-being of patients with hypertension. Challenges with adherence are common and associated with clinical, behavioural and psychosocial factors. This study sought to provide data on the extent of medication adherence among male patients with hypertension and their biopsychosocial predictors. Patient and clinical characteristics, psychological distress, insomnia and sexual dysfunction were hypothesized to predict outcomes of medication adherence. Utilizing quantitative data from a hospital-based cross-sectional study from 358 male out-patients with hypertension attending a tertiary hospital in Ghana, medication adherence was associated with age, marital status, educational level, income, duration of diagnosis, number of medications taken and sexual dysfunction. These findings support the need for biopsychosocial interventions aiming at promoting adherence while taking these factors into consideration for the benefit of improving the health and general well-being of male patients with hypertension.
药物依从性是反映高血压患者健康和整体健康状况的一个关键健康结果。药物依从性方面的挑战很常见，与临床、行为和社会心理因素有关。本研究旨在提供关于高血压男性患者药物依从性程度及其生物心理预测因素的数据。假设患者和临床特征、心理困扰、失眠和性功能障碍可预测药物依从性结果。利用来自加纳一家三级医院 358 名高血压男性门诊患者的基于医院的横断面研究的定量数据，药物依从性与年龄、婚姻状况、教育程度、收入、诊断持续时间、服用药物的数量和性功能障碍有关。这些发现支持需要进行生物心理社会干预，旨在促进依从性，同时考虑这些因素，以改善高血压男性患者的健康和整体幸福感。
