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[测定动脉高血压患者钠-锂逆向转运的临床重要性]

[Clinical importance of determining Na-Li countertransport in patients with arterial hypertension].

作者信息

Eliseev A O, Petrov V V, Arabidze G G, Kaĭkov M I, Kukharchuk V V

出版信息

Kardiologiia. 1988 Aug;28(8):26-30.

PMID:3199650
Abstract

Erythrocyte Na-Li countertransport was assessed in 99 patients with various arterial hypertensions. Mean Na-Li countertransport rate was 476 +/- 43 mumol/l 1 cells/hour in essential hypertension, or nearly twice as high as mean rates for hypertensive chronic diffuse glomerulonephritis, chronic pyelonephritis, renovascular hypertension and nonspecific aortoarteritis, primarily affecting extracranial arteries. In 2 patients, operated on for renal arterial stenosis, Na-Li countertransport was high and the operation had no hypotensive effect, suggesting that renal arterial stenosis was combined with essential hypertension. In 1 patient, the original diagnosis of chronic diffuse glomerulonephritis and aldosteronoma was not confirmed at surgery and renal biopsy, and the diagnosis of essential hypertension was made instead.

摘要

对99例患有各种动脉性高血压的患者进行了红细胞钠-锂逆向转运评估。原发性高血压患者的平均钠-锂逆向转运速率为476±43微摩尔/升/1细胞/小时,几乎是高血压慢性弥漫性肾小球肾炎、慢性肾盂肾炎、肾血管性高血压和主要影响颅外动脉的非特异性主动脉动脉炎平均速率的两倍。在2例因肾动脉狭窄接受手术的患者中,钠-锂逆向转运较高,手术无降压作用,提示肾动脉狭窄合并原发性高血压。在1例患者中,手术和肾活检未证实最初诊断的慢性弥漫性肾小球肾炎和醛固酮瘤,取而代之的是原发性高血压的诊断。

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Nonlinear relationship between erythrocyte sodium-lithium countertransport and blood pressure in man.人体红细胞钠-锂逆向转运与血压之间的非线性关系。
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