Alkhouli Mohamad, Osman Mohammed, Elsisy Mohamed Farouk A, Kawsara Akram, Berzingi Chalak O
Department of Cardiovascular Diseases, Mayo Clinic School of Medicine, 200 1st Street SW, Rochester, MN, 55905, USA.
Division of Cardiology, West Virginia University School of Medicine, Morgantown, WV, USA.
Curr Treat Options Cardiovasc Med. 2020 Jan 30;22(2):4. doi: 10.1007/s11936-020-0804-6.
To provide a contemporary concise overview of the currently available mechanical circulatory support (MCS) devices and the emerging concepts in the management of cardiogenic shock (CS).
New classification of CS has emerged and is hoped to allow a unified approach to research and clinical management of CS. A number of MCS devices have also become available for clinical use in the last 2 decades. Those devices have different hemodynamic targets, provide various levels of support, and are associated with specific requirements and potential complications. Data on the utility of MCS in CS remains conflicting with randomized trials showing no benefit of MCS, and observational data suggesting an incremental value for MCS over medical therapy. However, the early use and escalation of MCS in a standardized approach do appear to provide a remarkable improvement in short-term outcomes of patients with CS. MCS devices afforded lifesaving treatment for many patients with CS. However, optimal utilization of such devices requires familiarity with their clinical data, and technical characteristics, and mandates their integration in an algorithmic team-based approach to CS.
对当前可用的机械循环支持(MCS)设备以及心源性休克(CS)管理中的新兴概念提供当代简明概述。
CS出现了新的分类,有望为CS的研究和临床管理提供统一方法。在过去20年中,一些MCS设备也已可供临床使用。这些设备具有不同的血流动力学目标,提供不同程度的支持,并与特定要求和潜在并发症相关。关于MCS在CS中的效用的数据仍然相互矛盾,随机试验显示MCS无益处,而观察性数据表明MCS比药物治疗具有更大价值。然而,以标准化方法早期使用和升级MCS似乎确实能显著改善CS患者的短期结局。MCS设备为许多CS患者提供了挽救生命的治疗。然而,要最佳利用此类设备,需要熟悉其临床数据和技术特征,并要求将它们整合到基于算法的团队CS治疗方法中。