Ainerua Martins O, Erhunmwunse Nosakhare, Tongo Isioma, Ezemonye Lawrence
Ecotoxicology and Environmental Forensic Laboratory, Department of Animal and Environmental Biology, Faculty of Life Sciences, University of Benin, PMB 1154, Benin City, Edo State Nigeria.
Toxicol Res. 2019 Nov 26;36(1):45-58. doi: 10.1007/s43188-019-00001-9. eCollection 2020 Jan.
Food toxicity assessment was made for frequently consumed canned foods in Nigeria in order to estimate potential human health risks associated with their consumption. Levels of heavy metals (Pb, Cd, As, Fe, Mn and Zn), Nitrate and Nitrite, pH and salt were assessed in randomly purchased samples from groceries stores to represent what is readily available on the market. Nitrates and nitrites were assessed using a Perkin-Elmer spectrophotometer while heavy metal levels were determined using Atomic absorption spectrophotometer. Human health risk was estimated using standard indices; estimated daily intake (EDI), target hazard quotient (THQ), hazard index (HI) and dietary exposure (DE). Results showed varying concentrations of nitrates, nitrites, heavy metals, in all the canned food categories but the level of salt and pH seemed constant. Nitrate, Fe and Cd in all the canned food categories exceeded recommended limit set by EU. Health risk estimations showed EDI values for Cd in all the canned food categories above the tolerable daily intake, while DE for Fe in canned sweet corn, Fe, Zn and Pb in canned beans/peas had values above recommended limits. THQ values for all the canned foods were above 1 in the canned beans/peas while HI was above 1 in the canned fish category. The study revealed the potential for Cd toxicity and risk of non-carcinogenic health effects from canned beans/peas consumption. Constant monitoring of canned foods is therefore imperative considering the growing demand for canned products due to changing lifestyle.
对尼日利亚经常食用的罐装食品进行了食品毒性评估，以估计食用这些食品对人类健康的潜在风险。从杂货店随机购买样品，评估其中重金属（铅、镉、砷、铁、锰和锌）、硝酸盐和亚硝酸盐、pH值和盐分的含量，以代表市场上 readily available 的产品情况。使用珀金埃尔默分光光度计评估硝酸盐和亚硝酸盐，使用原子吸收分光光度计测定重金属含量。使用标准指标估计人类健康风险；估计每日摄入量（EDI）、目标危害商数（THQ）、危害指数（HI）和膳食暴露量（DE）。结果显示，所有罐装食品类别中硝酸盐、亚硝酸盐、重金属的浓度各不相同，但盐分和pH值水平似乎恒定。所有罐装食品类别中的硝酸盐、铁和镉均超过了欧盟设定的推荐限值。健康风险评估显示，所有罐装食品类别中镉的EDI值均高于可耐受每日摄入量，而罐装甜玉米中铁的DE值、罐装豆类/豌豆中铁、锌和铅的DE值均高于推荐限值。罐装豆类/豌豆中所有罐装食品的THQ值均高于1，而罐装鱼类中的HI值高于1。该研究揭示了食用罐装豆类/豌豆存在镉毒性的可能性和非致癌健康影响的风险。因此，考虑到由于生活方式的改变对罐装产品的需求不断增加，对罐装食品进行持续监测势在必行。
