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复杂重建技术应用于晚期头颈癌。

Complex reconstruction technique applied in advanced head and neck cancer.

作者信息

Gan Weigang, Xiang Yu, Lv Dan, Liu Jun, Wang Haiyang, Deng Di, Wang Ji, Li Linke, Ma Tengfei, Liu Shixi, Chen Fei

机构信息

Department of Otorhinolaryngology-Head and Neck Surgery, West China Hospital, West China School of Medicine, Sichuan University, Chengdu.

Morphometric Research Laboratory, North Sichuan Medical College, Nanchong, Sichuan, China.

出版信息

Medicine (Baltimore). 2020 Jan;99(5):e18810. doi: 10.1097/MD.0000000000018810.

DOI:10.1097/MD.0000000000018810
PMID:32000381
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7004775/
Abstract

Complex reconstruction skills in advanced head and neck cancer (HNC) could resolve the key problem of large defects after tumor resection. We combined the anterolateral thigh free flap, fascia lata flap, and greater saphenous vein graft in the reconstruction process of salvage surgery. Seven patients suffering from advanced HNC who experienced the failure of multiple therapeutic methods were enrolled in our study between June 2017 and January 2018. They all agreed to voluntarily undergo the tumor excision and complex reconstruction procedure we developed. The total flap size ranged from 20 × 13 cm to 30 × 15 cm. The length of the greater saphenous vein graft ranged from 4 to 11 cm. The hospitalization period ranged from 7 to 33 days. All of the flaps were viable, but in 1 patient, oral flap edge infection and necrosis necessitated partial debridement on day 7 postoperatively. All donor sites were closed primarily. We report our experience with this surgical method for complex reconstruction in advanced HNC patients.

摘要

晚期头颈癌(HNC)的复杂重建技术可解决肿瘤切除后大缺损的关键问题。我们在挽救性手术的重建过程中联合应用了股前外侧游离皮瓣、阔筋膜张肌皮瓣和大隐静脉移植。2017年6月至2018年1月,我们纳入了7例经历多种治疗方法失败的晚期HNC患者。他们均自愿同意接受我们开展的肿瘤切除及复杂重建手术。皮瓣总面积为20×13cm至30×15cm。大隐静脉移植长度为4至11cm。住院时间为7至33天。所有皮瓣均存活,但1例患者在术后第7天出现口腔皮瓣边缘感染和坏死,需要进行部分清创。所有供区均一期缝合。我们报告了这种手术方法用于晚期HNC患者复杂重建的经验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5815/7004775/34731b070e68/medi-99-e18810-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5815/7004775/990207767bb4/medi-99-e18810-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5815/7004775/34731b070e68/medi-99-e18810-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5815/7004775/990207767bb4/medi-99-e18810-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5815/7004775/34731b070e68/medi-99-e18810-g002.jpg

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本文引用的文献

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Head and neck cancer: improving outcomes with a multidisciplinary approach.头颈癌:采用多学科方法改善治疗效果
Cancer Manag Res. 2017 Aug 18;9:363-371. doi: 10.2147/CMAR.S115761. eCollection 2017.
2
Combined Anterolateral Thigh and Tensor Fasciae Latae Flaps: An Option for Reconstruction of Large Head and Neck Defects.股前外侧肌皮瓣联合阔筋膜张肌皮瓣:一种修复大型头颈部缺损的选择。
J Oral Maxillofac Surg. 2017 Aug;75(8):1743-1751. doi: 10.1016/j.joms.2016.12.025. Epub 2016 Dec 26.
3
Epidemiology of coronary heart disease and acute coronary syndrome.
冠心病和急性冠脉综合征的流行病学。
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Management of anterior skull base defect depending on its size and location.根据前颅底缺损的大小和位置进行处理。
Biomed Res Int. 2014;2014:346873. doi: 10.1155/2014/346873. Epub 2014 May 7.
5
Prophylactic chimera anterolateral thigh/vastus lateralis flap: preventing complications in high-risk head and neck reconstruction.预防性嵌合股前外侧/股外侧肌皮瓣:预防高危头颈重建中的并发症
J Oral Maxillofac Surg. 2014 May;72(5):1013-22. doi: 10.1016/j.joms.2013.11.010. Epub 2013 Nov 21.
6
Tripaddled anterolateral thigh flap for simultaneous reconstruction of bilateral buccal defects after buccal cancer ablation and severe oral submucous fibrosis release: a case report.三蒂股前外侧皮瓣同期修复颊癌切除及重度口腔黏膜下纤维化松解术后双侧颊部缺损:1例报告
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