Influenza Division, U.S. Centers for Disease Control and Prevention, Hanoi, Viet Nam.
Influenza Division, U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA.
Vaccine. 2020 Feb 18;38(8):2045-2050. doi: 10.1016/j.vaccine.2019.12.047. Epub 2020 Jan 27.
A demonstration project in Vietnam provided 11,000 doses of human seasonal influenza vaccine free of charge to healthcare workers (HCWs) in 4 provinces of Vietnam. Through this project, we conducted an acceptability survey to identify the main reasons that individuals chose to be vaccinated or not to inform and improve future immunization activities.
We conducted a descriptive cross-sectional survey from May to August 2017 among HCWs at 13 selected health facilities. We employed logistic regression to determine the association between demographic and professional factors, and the decision to receive seasonal influenza vaccine. We performed post-hoc pairwise comparisons among reasons for and against vaccination using Chi square and Fisher's exact tests (for cell sizes <5).
A total of 1,450 HCWs participated in the survey, with a higher proportion of females than males (74% versus 26%). The median age of the participating HCWs was 35 years (median range 25.8-44.2). Among those surveyed, 700 (48%) HCWs were vaccinated against seasonal influenza during the first half of 2017. Younger HCWs under 30 and 30-39 years old were less likely to get vaccinated against seasonal influenza than HCWs ≥50 years old (OR = 0.5; 95%CI 0.4-0.8 and OR = 0.6; 95%CI 0.4-0.8 respectively). Nurses and other employees were more likely to get seasonal influenza vaccination than physicians (OR = 1.5; 95%CI 1.0-2.4 and OR = 2.0; 95%CI 1.2-3.2 respectively). The most common reason for accepting vaccination was fear of getting influenza (66%) and the most common reason for not getting vaccinated was concern about vaccine side effects (23%).
Acceptability of seasonal influenza vaccines in this setting varied among HCWs by age group and job category. Interventions to increase acceptance of vaccine among HCWs in this setting where influenza vaccine is being introduced free for the first time should include targeted risk communication on vaccine safety and efficacy.
越南的一个示范项目向越南 4 个省的医护人员免费提供了 11000 剂季节性流感疫苗。通过这个项目，我们进行了一项可接受性调查，以确定个人选择接种或不接种的主要原因，从而为未来的免疫接种活动提供信息和改进。
我们在 2017 年 5 月至 8 月期间在 13 个选定的卫生机构对医护人员进行了一项描述性的横断面调查。我们采用逻辑回归来确定人口统计学和职业因素与接受季节性流感疫苗之间的关联。我们使用卡方检验和 Fisher 精确检验（对于细胞大小 <5）对赞成和反对接种的原因进行了事后两两比较。
共有 1450 名医护人员参加了调查，其中女性多于男性（74%对 26%）。参与调查的医护人员的中位年龄为 35 岁（中位数范围为 25.8-44.2）。在调查的人群中，2017 年上半年有 700 名（48%）医护人员接种了季节性流感疫苗。30 岁以下和 30-39 岁的年轻医护人员接种季节性流感疫苗的可能性低于 50 岁以上的医护人员（OR=0.5；95%CI 0.4-0.8 和 OR=0.6；95%CI 0.4-0.8）。护士和其他员工比医生更有可能接种季节性流感疫苗（OR=1.5；95%CI 1.0-2.4 和 OR=2.0；95%CI 1.2-3.2）。接受接种的最常见原因是担心感染流感（66%），不接种的最常见原因是担心疫苗的副作用（23%）。
在这个背景下，医护人员对季节性流感疫苗的可接受性因年龄组和工作类别而异。在这个首次免费提供流感疫苗的背景下，为提高医护人员对疫苗的接受程度，应针对疫苗的安全性和有效性进行有针对性的风险沟通。
