Centre for Health Economics, University of York, York, UK.
Health Econ. 2020 May;29(5):567-579. doi: 10.1002/hec.4003. Epub 2020 Jan 30.
Alternative strategies can reduce road vehicle emissions, with differential effects on exposure across population groups. We compare alternative strategies in West Yorkshire using a framework for economic evaluation that considers multiple perspectives and that takes account of the distribution of health outcomes. Exposure to pollutants by area is converted, via dose response relationships, into disease averted. Health benefits and National Health Service costs from diseases are estimated conditional on population demographics and index of multiple deprivation. The net health benefits from alternative strategies are expressed as distributions of quality-adjusted life expectancy (QALE), which are compared using dominance criteria and societal aversion to health inequality. Net production is estimated from intervention costs and the effects of health improvement on production and consumption. Social care outcomes are estimated from health improvement among care recipients and changes in care expenditure. A switch to less polluting private vehicles is dominant in terms of the distribution of QALE and social care outcomes but not consumption. Inclusion of health inequality aversion alters the rank order compared with prioritisation on health maximisation. The results were sensitive to the magnitude of health opportunity costs, the level of inequality aversion, and the proportion of intervention cost that generates health opportunity cost.
替代策略可以减少道路车辆排放,对不同人群的暴露有不同的影响。我们使用考虑多种观点并考虑健康结果分布的经济评估框架来比较西约克郡的替代策略。通过剂量反应关系,将污染物暴露的区域转换为避免的疾病。根据人口统计学和多种剥夺指数,估计了疾病的健康效益和国民保健服务成本。替代策略的净健康效益表示为质量调整生命期望(QALE)的分布,使用优势标准和社会对健康不平等的厌恶进行比较。从干预成本和健康改善对生产和消费的影响来估计净产量。从接受护理者的健康改善和护理支出的变化来估计社会护理结果。从减少污染的私人车辆的转变在 QALE 和社会护理结果方面占主导地位,但在消费方面则不然。纳入健康不平等厌恶会改变与健康最大化优先级相比的排名顺序。结果对健康机会成本的大小、不平等厌恶的程度以及产生健康机会成本的干预成本比例很敏感。