• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

横断面研究:巴西亚马孙地区社区居住老年人肺功能与肌肉减少症的关系。

Cross-Sectional Study on the Association between Pulmonary Function and Sarcopenia in Brazilian Community-Dwelling Elderly from the Amazon Region.

机构信息

Maycon Sousa Pegorari, Federal University of Amapá, Department of biological and health sciences, Physical Therapy Course. Address: Road Juscelino Kubitschek, Km - 02, Jardim Marco Zero, Macapá - AP, CEP 68903-419 - Phone number: (+55 96) 4009-2944 E-mail:

出版信息

J Nutr Health Aging. 2020;24(2):181-187. doi: 10.1007/s12603-019-1290-y.

DOI:10.1007/s12603-019-1290-y
PMID:32003408
Abstract

OBJECTIVES

To compare the obtained and expected values of pulmonary function variables between sarcopenic and non-sarcopenic elderly; verify the association between the pulmonary function and the indicators and diagnosis of sarcopenia; and establish cut-off points for pulmonary function variables to predict sarcopenia.

DESIGN

Cross-sectional study.

LOCATION

Macapá, Brazil.

PARTICIPANTS

community-dwelling elderly ≥ 60 years old (n=383), both sexes.

MEASURES

Were evaluated according to variables of pulmonary function (spirometry) and sarcopenia, according to the EWGSOP consensus. The association between pulmonary function and sarcopenia was performed using logistic regression and cut-off points established from the ROC Curve.

RESULTS

The prevalence of sarcopenia was 12.53% (n = 48). Sarcopenic individuals had significantly lower mean values for FVC, FEV1, FEF25-75% and PEF than non-sarcopenic. After adjustment, spirometric variables were inversely associated with sarcopenia (the increase by one unit of liter in FVC, FEV1 and FEF25-75% decreased the probability of sarcopenia by 59%, 67% and 39%, respectively), and the majority of these variables with the muscular strength indicator. Cut-off points, for elderly men and women, were discriminant criteria for the presence of sarcopenia: FVC (≤2.52 L and ≤1.82 L), FEV1 (≤2.1 L and ≤1.39 L), PEF (≤3.45 L/s and ≤2.93 L/s) and FEF5-75% (≤1.97 L/s and ≤1.74 L/s).

CONCLUSIONS

There was loss of pulmonary function in sarcopenic elderly patients and an inverse association with the diagnosis of sarcopenia and its indicators. Cut-off points of pulmonary function variables can be used as a useful tool to discriminate sarcopenia.

摘要

目的

比较肌少症和非肌少症老年人的肺功能变量的实测值和预期值;验证肺功能与肌少症指标和诊断之间的关系;并建立肺功能变量的截断值来预测肌少症。

设计

横断面研究。

地点

巴西马卡帕。

参与者

≥ 60 岁的社区居住老年人(n=383),男女不限。

措施

根据肺功能(肺活量测定法)和肌少症的变量进行评估,符合 EWGSOP 共识。使用逻辑回归和 ROC 曲线建立截断值来评估肺功能与肌少症之间的关系。

结果

肌少症的患病率为 12.53%(n=48)。与非肌少症者相比,肌少症患者的 FVC、FEV1、FEF25-75%和 PEF 的平均值明显较低。调整后,肺活量测定变量与肌少症呈负相关(FVC、FEV1 和 FEF25-75%每增加一个单位,肌少症的可能性分别降低 59%、67%和 39%),且大多数与肌肉力量指标相关。对于老年男性和女性,截断值是存在肌少症的判别标准:FVC(≤2.52 L 和≤1.82 L)、FEV1(≤2.1 L 和≤1.39 L)、PEF(≤3.45 L/s 和≤2.93 L/s)和 FEF5-75%(≤1.97 L/s 和≤1.74 L/s)。

结论

肌少症老年患者存在肺功能下降,与肌少症及其指标的诊断呈负相关。肺功能变量的截断值可作为鉴别肌少症的有用工具。

相似文献

1
Cross-Sectional Study on the Association between Pulmonary Function and Sarcopenia in Brazilian Community-Dwelling Elderly from the Amazon Region.横断面研究:巴西亚马孙地区社区居住老年人肺功能与肌肉减少症的关系。
J Nutr Health Aging. 2020;24(2):181-187. doi: 10.1007/s12603-019-1290-y.
2
Respiratory Muscle Strength as a Discriminator of Sarcopenia in Community-Dwelling Elderly: A Cross-Sectional Study.呼吸肌力量作为社区居住老年人肌少症的鉴别指标:一项横断面研究。
J Nutr Health Aging. 2018;22(8):952-958. doi: 10.1007/s12603-018-1079-4.
3
Anthropometric indicators as a discriminator of sarcopenia in community-dwelling older adults of the Amazon region: a cross-sectional study.人体测量指标作为亚马逊地区社区居住的老年人群肌少症的鉴别指标:一项横断面研究。
BMC Geriatr. 2020 Dec 1;20(1):518. doi: 10.1186/s12877-020-01923-y.
4
Physical function-derived cut-points for the diagnosis of sarcopenia and dynapenia from the Canadian longitudinal study on aging.基于身体功能的加拿大老龄化纵向研究中肌少症和无力症诊断切点
J Cachexia Sarcopenia Muscle. 2019 Oct;10(5):985-999. doi: 10.1002/jcsm.12462. Epub 2019 Jul 15.
5
Accuracy of handgrip and respiratory muscle strength in identifying sarcopenia in older, community-dwelling, Brazilian women.手握力和呼吸肌力量在识别老年、社区居住的巴西女性肌少症中的准确性。
Sci Rep. 2023 Jan 27;13(1):1553. doi: 10.1038/s41598-023-28549-5.
6
Pulmonary Function as a Predictor of Frailty Syndrome in Community-Dwelling Older Adults.肺功能作为社区居住的老年人群衰弱综合征的预测指标。
J Geriatr Phys Ther. 2023;46(1):64-70. doi: 10.1519/JPT.0000000000000315. Epub 2021 Jun 2.
7
Peak Expiratory Flow as an Index of Frailty Syndrome in Older Adults: A Cross-Sectional Study.呼气峰值流量作为老年人衰弱综合征的指标:一项横断面研究。
J Nutr Health Aging. 2020;24(9):993-998. doi: 10.1007/s12603-020-1423-3.
8
Are maximum respiratory pressures predictors of sarcopenia in the elderly?最大呼吸压力能否预测老年人的肌肉减少症?
J Bras Pneumol. 2022 Feb 2;48(1):e20210335. doi: 10.36416/1806-3756/e20210335. eCollection 2022.
9
Relationship Between Sarcopenia and Frailty in the Toledo Study of Healthy Aging: A Population Based Cross-Sectional Study.《托莱多健康老龄化研究:肌肉减少症与虚弱之间的关系:一项基于人群的横断面研究》。
J Am Med Dir Assoc. 2018 Apr;19(4):282-286. doi: 10.1016/j.jamda.2017.09.014. Epub 2017 Nov 1.
10
Definition of Respiratory Sarcopenia With Peak Expiratory Flow Rate.呼吸性消瘦的定义与最大呼气流量率。
J Am Med Dir Assoc. 2019 Aug;20(8):1021-1025. doi: 10.1016/j.jamda.2018.12.013. Epub 2019 Feb 6.

引用本文的文献

1
The association between muscle strength and z scores of pulmonary function.肌肉力量与肺功能z评分之间的关联。
Sci Rep. 2025 Jul 29;15(1):27662. doi: 10.1038/s41598-025-13371-y.
2
The Impact of Sarcopenia on Early Postoperative Complications in Patients Undergoing Decortication due to Empyema: A Retrospective Study in Turkey.肌肉减少症对因脓胸行胸膜剥脱术患者术后早期并发症的影响:土耳其的一项回顾性研究
J Chest Surg. 2025 Jul 5;58(4):148-156. doi: 10.5090/jcs.24.086. Epub 2025 Mar 14.
3
Association between sarcopenia and outcomes of surgically treated oral squamous cell carcinoma: a systematic review and meta-analysis.

本文引用的文献

1
Respiratory Muscle Strength as a Discriminator of Sarcopenia in Community-Dwelling Elderly: A Cross-Sectional Study.呼吸肌力量作为社区居住老年人肌少症的鉴别指标:一项横断面研究。
J Nutr Health Aging. 2018;22(8):952-958. doi: 10.1007/s12603-018-1079-4.
2
Skeletal muscle ex vivo mitochondrial respiration parallels decline in vivo oxidative capacity, cardiorespiratory fitness, and muscle strength: The Baltimore Longitudinal Study of Aging.骨骼肌线粒体呼吸在体外观测与在体氧化能力、心肺功能适应性和肌肉力量的下降呈平行关系:巴尔的摩纵向衰老研究。
Aging Cell. 2018 Apr;17(2). doi: 10.1111/acel.12725. Epub 2018 Jan 21.
3
Sarcopenia in chronic obstructive pulmonary disease: A study of prevalence and associated factors in the Southeast Asian population.
肌肉减少症与手术治疗的口腔鳞状细胞癌预后之间的关联:一项系统评价和荟萃分析。
Front Oncol. 2024 Nov 1;14:1445956. doi: 10.3389/fonc.2024.1445956. eCollection 2024.
4
Anthropometric equation has sufficient diagnostic capacity to identify sarcopenia in women with breast cancer.人体测量方程式具有足够的诊断能力,可用于识别患有乳腺癌的女性中的肌肉减少症。
BMC Cancer. 2024 Oct 24;24(1):1310. doi: 10.1186/s12885-024-12921-3.
5
Estrogen Status Influences Whole-Body Vibration Training-Induced Improvements on Muscle Mass and Strength in Female Ovariectomized Mice.雌激素水平影响全身振动训练对去卵巢雌性小鼠肌肉质量和力量的改善作用。
Int J Med Sci. 2024 Aug 12;21(11):2149-2157. doi: 10.7150/ijms.97770. eCollection 2024.
6
Establishing an optimal diagnostic criterion for respiratory sarcopenia using peak expiratory flow rate.使用呼气峰流速率建立呼吸肌少症的最佳诊断标准。
Aging Clin Exp Res. 2024 May 23;36(1):116. doi: 10.1007/s40520-024-02765-z.
7
Skeletal muscle mass obtained by anthropometric equation and presence of sarcopenia in postmenopausal women.通过人体测量方程获得的骨骼肌质量和绝经后妇女的肌少症存在。
Rev Bras Ginecol Obstet. 2024 Mar 15;46. doi: 10.61622/rbgo/2024AO09. eCollection 2024.
8
Cognition as mediator of pulmonary function and risk of sarcopenia among older adults.认知作为老年人肺功能和肌肉减少症风险的中介。
BMC Public Health. 2024 May 18;24(1):1347. doi: 10.1186/s12889-024-18848-5.
9
Association of Pulmonary Function with Osteosarcopenic Obesity in Older Adults Aged over 50 Years.老年人中肺功能与肌少性肥胖性骨量减少症的相关性。
Nutrients. 2023 Jun 28;15(13):2933. doi: 10.3390/nu15132933.
10
Chest CT opportunistic biomarkers for phenotyping high-risk COVID-19 patients: a retrospective multicentre study.胸部 CT 机会性生物标志物用于表型分析 COVID-19 高危患者:一项回顾性多中心研究。
Eur Radiol. 2023 Nov;33(11):7756-7768. doi: 10.1007/s00330-023-09702-0. Epub 2023 May 11.
慢性阻塞性肺疾病中的肌肉减少症:东南亚人群中的患病率及相关因素研究。
Chron Respir Dis. 2018 Aug;15(3):250-257. doi: 10.1177/1479972317743759. Epub 2017 Nov 29.
4
Relationships among peak expiratory flow rate, body composition, physical function, and sarcopenia in community-dwelling older adults.社区居住的老年人中呼气峰值流速、身体成分、身体功能和肌肉减少症之间的关系。
Aging Clin Exp Res. 2018 Apr;30(4):331-340. doi: 10.1007/s40520-017-0777-9. Epub 2017 May 30.
5
Respiratory muscle strength in relation to sarcopenia in elderly cardiac patients.老年心脏病患者呼吸肌力量与肌肉减少症的关系
Aging Clin Exp Res. 2016 Dec;28(6):1143-1148. doi: 10.1007/s40520-016-0534-5. Epub 2016 Jan 22.
6
"Chair Stand Test" as Simple Tool for Sarcopenia Screening in Elderly Women.“椅子站立测试”作为老年女性肌肉减少症筛查的简易工具
J Nutr Health Aging. 2016 Jan;20(1):56-9. doi: 10.1007/s12603-016-0676-3.
7
Sarcopenia in COPD: relationship with COPD severity and prognosis.慢性阻塞性肺疾病中的肌肉减少症:与慢性阻塞性肺疾病严重程度及预后的关系
J Bras Pneumol. 2015 Sep-Oct;41(5):415-21. doi: 10.1590/S1806-37132015000000040.
8
Implication of Sarcopenia and Sarcopenic Obesity on Lung Function in Healthy Elderly: Using Korean National Health and Nutrition Examination Survey.肌肉减少症和肌肉减少性肥胖对健康老年人肺功能的影响:基于韩国国民健康与营养检查调查
J Korean Med Sci. 2015 Nov;30(11):1682-8. doi: 10.3346/jkms.2015.30.11.1682. Epub 2015 Oct 16.
9
Functional impact of sarcopenia in respiratory muscles.肌肉减少症对呼吸肌的功能影响。
Respir Physiol Neurobiol. 2016 Jun;226:137-46. doi: 10.1016/j.resp.2015.10.001. Epub 2015 Oct 20.
10
Relation between systemic inflammatory markers, peripheral muscle mass, and strength in limb muscles in stable COPD patients.稳定期慢性阻塞性肺疾病(COPD)患者全身炎症标志物、外周肌肉质量与肢体肌肉力量之间的关系。
Int J Chron Obstruct Pulmon Dis. 2015 Aug 6;10:1553-8. doi: 10.2147/COPD.S85954. eCollection 2015.