Global Fund to Fight AIDS, Tuberculosis and Malaria. Geneva.
World Health Organization. Geneva, Switzerland.
Int J Tuberc Lung Dis. 2020 Jan 1;24(1):22-27. doi: 10.5588/ijtld.19.0376.
Drug-resistant tuberculosis (DR-TB) constitutes a global threat and a major contributor to deaths related to antimicrobial resistance. Despite progress in DR-TB detection and treatment over the last decade, huge gaps remain in treatment coverage, access to quality care and treatment outcome. Global Fund investments have been critical to scaling up the existing and new diagnostic tools, treatment coverage and people-centred service delivery. The United Nations General Assembly (UNGA) high-level meeting represents unprecedented opportunities to accelerate towards addressing DR-TB. Established in 2000 and funded by the Global Fund since 2009, the Green Light Committee (GLC) mechanism has evolved from project approval to providing demand-based technical assistance to countries to scale up response to DR-TB based on their need and priorities. Lessons learnt from the GLC mechanism over 10 years demonstrate that a result-based, systematic and accountable technical assistance model to support scale-up of DR-TB response is critically important. Meeting the UNGA declaration targets requires major scale-up of current efforts and new tools, and hence the need for predictable, consistent and sustained technical support to countries, including through the regional GLC mechanism. The application of the principles and processes of this model could be adapted and replicated to design a similar performance-based and quality-assured technical support mechanism.
耐多药结核病(DR-TB)构成了全球性威胁,也是导致与抗微生物药物耐药相关死亡的主要原因之一。尽管在过去十年中,DR-TB 的检测和治疗取得了进展,但在治疗覆盖面、获得优质护理和治疗结果方面仍存在巨大差距。全球基金的投资对于扩大现有和新的诊断工具、治疗覆盖面以及以患者为中心的服务提供至关重要。联合国大会(UNGA)高级别会议代表着加快解决耐多药结核病问题的前所未有的机会。绿色信号灯委员会(GLC)机制成立于 2000 年,自 2009 年以来一直由全球基金供资,该机制已经从项目审批演变为根据各国的需求和优先事项,为扩大耐多药结核病应对提供基于需求的技术援助。10 年来,从 GLC 机制中吸取的经验教训表明,基于成果、系统和问责的技术援助模式对于支持扩大耐多药结核病应对至关重要。要实现联合国大会宣言的目标,需要大幅扩大当前的努力和新工具,因此需要向各国提供可预测、持续和稳定的技术支持,包括通过区域 GLC 机制提供这种支持。该模式的原则和流程可以进行调整和复制,以设计类似的基于绩效和质量保证的技术支持机制。