Early Psychosis Intervention Center, Region Zealand Psychiatry, Roskilde, Denmark.
Mental Health Center Amager, Copenhagen, Denmark.
Schizophr Res. 2020 Apr;218:116-123. doi: 10.1016/j.schres.2020.01.022. Epub 2020 Jan 29.
Self-alienation is a common characterization of various disturbing experiences in patients with schizophrenia. A vivid example comes from patient reports of not recognizing themselves when inspecting their specular image in the mirror. By applying the multisensory paradigm of the Enfacement Illusion, this study empirically addresses the specular Self-Other discrimination in patients with schizophrenia. 35 patients diagnosed with schizophrenia and 35 healthy matched controls were enrolled in the study. Results found that the group of patients with schizophrenia had a significant skewed self-other discrimination towards the other at baseline. Furthermore, the effect of visuo-tactile stimulation on self-recognition in the schizophrenia patients was significantly altered after both synchronous and asynchronous stimulation compared to baseline. This contrasted with healthy controls which in line with earlier studies only had significantly different self-recognition after synchronous stimulation. The study thus suggests that patients with schizophrenia have deviations in their specular self-recognition compared to healthy controls. Moreover, that temporal factors in multisensory integration may contribute to alterations of self-related stimuli in patients with schizophrenia.
自我异化是精神分裂症患者各种困扰体验的常见特征。一个生动的例子来自于患者在镜子里检查自己的镜像时，报告说认不出自己。通过应用面部错觉的多感觉范式，本研究实证研究了精神分裂症患者的镜像自我-他人辨别。研究招募了 35 名被诊断为精神分裂症的患者和 35 名健康匹配的对照组。结果发现，精神分裂症患者组在基线时对他人的自我-他人辨别存在明显的偏斜。此外，与基线相比，精神分裂症患者在同步和异步刺激后，对自我识别的视触刺激的影响发生了显著改变。这与健康对照组形成了对比，正如早期研究表明，只有在同步刺激后，健康对照组的自我识别才会有显著差异。因此，该研究表明，与健康对照组相比，精神分裂症患者的镜像自我识别存在偏差。此外，多感觉整合中的时间因素可能导致精神分裂症患者的自我相关刺激发生改变。
