Department of Child Psychiatry, Shenzhen Kangning Hospital, Shenzhen, 518003, China.
Shenzhen Kangning Hospital, Shenzhen University, Shenzhen, 518061, China.
J Autism Dev Disord. 2020 Apr;50(4):1249-1257. doi: 10.1007/s10803-019-04256-x.
The objective of this meta-analysis was to assess the dental health status of children with ASD in terms of decayed, missing, and filled permanent teeth (DMFT) and decayed, missing, and filled deciduous teeth (dmft). PubMed, Embase, psycINFO, and Cochrane library were searched for studies published until September 2018. A random-effects model was applied to estimate the pooled results.Nine studies comprising 532 children with ASD and 622 controls were included. No significant differences between children with ASD and controls were observed for DMFT and dmft in the world. Subgroup analyses revealed that children with ASD had a significantly higher dmft index than that of controls in Asia.Children with ASD have a worse dental health status than healthy children in Asia, but caution is necessary given the limited studies available for analysis.
本荟萃分析的目的是评估自闭症谱系障碍（ASD）儿童的口腔健康状况，包括恒牙的龋齿、缺失和充填（DMFT）以及乳牙的龋齿、缺失和充填（dmft）。检索了截至 2018 年 9 月发表的 PubMed、Embase、psycINFO 和 Cochrane 图书馆的研究。应用随机效应模型估计汇总结果。纳入了 9 项研究，共包括 532 名 ASD 儿童和 622 名对照。在世界范围内，ASD 儿童与对照组的 DMFT 和 dmft 之间无显著差异。亚组分析显示，亚洲地区 ASD 儿童的 dmft 指数显著高于对照组。亚洲地区 ASD 儿童的口腔健康状况比健康儿童差，但由于可供分析的研究有限，需要谨慎对待。
