Kreko Evelina, Kola Ermira, Sadikaj Festime, Dardha Blerta, Tushe Eduard
Service of Neonatology, University Hospital of Obstetrics and Gynecology "Koço Gliozheni", Tirana, Albania.
Department of Pediatrics, University Hospital Center "Nene Tereza", Tirana, Albania.
Open Access Maced J Med Sci. 2019 Oct 14;7(21):3592-3595. doi: 10.3889/oamjms.2019.832. eCollection 2019 Nov 15.
This study aims to compare the neonatal morbidity of Intrauterine growth restricted (IUGR) Late Preterm (LP) babies, to those born Late Preterm but evaluated as Appropriate for Gestational Age (AGA).
The study is a 2-year prospective one that used data from the Neonatal Intensive Care Unit (NICU) charts of LP neonates born in our tertiary maternity hospital "Koço Gliozheni" in Tirana. Congenital anomalies and genetical syndromes are excluded. Neonatal morbidity of IUGR Late Preterm is compared to those born Late Preterm but evaluated as AGA. OR and CI, 95% is calculated.
Out of 336 LP babies treated in NICU, 88 resulted with IUGR and 206 AGA used as a control group. We found significantly higher morbidity in the IUGR group for hypoglycemia, polycythemia, feeding intolerance, birth asphyxia and seizures, secondary sepsis have higher morbidity but the difference is not significant. No differences were found for hyperbilirubinemia in both groups. No neonatal deaths were observed in both groups.
Our study showed that late preterm IUGR has a significantly higher risk for neonatal morbidity when compared to late preterm AGA babies.
本研究旨在比较宫内生长受限(IUGR)的晚期早产儿与晚期早产但评估为适于胎龄(AGA)的新生儿的发病率。
该研究是一项为期2年的前瞻性研究,使用了我们位于地拉那的三级妇产医院“科乔·格廖泽尼”出生的晚期早产儿新生儿重症监护病房(NICU)图表中的数据。排除先天性异常和遗传综合征。将IUGR晚期早产儿的新生儿发病率与晚期早产但评估为AGA的新生儿进行比较。计算95%的OR和CI。
在NICU接受治疗的336例晚期早产儿中,88例为IUGR,206例AGA作为对照组。我们发现IUGR组在低血糖、红细胞增多症、喂养不耐受、出生窒息和惊厥方面的发病率显著更高,继发性败血症发病率更高,但差异不显著。两组在高胆红素血症方面未发现差异。两组均未观察到新生儿死亡。
我们的研究表明,与晚期早产AGA婴儿相比,晚期早产IUGR的新生儿发病风险显著更高。