Khusial Rishi J, Honkoop Persijn J, van der Meer Victor, Snoeck-Stroband Jiska B, Sont Jacob K
Dept of Biomedical Data Sciences, Section Medical Decision Making, Leiden University Medical Center, Leiden, The Netherlands.
ERJ Open Res. 2020 Jan 27;6(1). doi: 10.1183/23120541.00289-2019. eCollection 2020 Jan.
Several newly developed eHealth applications use online questionnaires to monitor asthma control. The Asthma Control Questionnaire (ACQ) and Asthma Quality of Life Questionnaire (AQLQ) are two such commonly used questionnaires. These questionnaires are validated for use on paper. This study aims to validate them by assessing the agreement between online and paper versions of the ACQ and AQLQ.
Patients (aged 18 years and older) from the Self-Management in Asthma Supported by Hospitals, ICT, Nurses and General Practitioners (SMASHING)-trial and Davos@home study were included in this study. Patients completed both the paper and online Dutch versions of the ACQ and AQLQ in a random order within a 2-week interval. Agreement between the different versions was assessed with paired t-tests, intraclass correlation coefficients and Bland-Altman plots.
In total 44 patients were eligible for analysis. The mean difference between the paper and online versions of the ACQ was 0.04 (p=0.40) and for the AQLQ it was 0.08 (p=0.06). The intraclass correlation coefficient scores were 0.94 for the ACQ and 0.95 for the AQLQ.
The online versions of the ACQ and AQLQ show high levels of agreement with the paper versions and can therefore be safely used in eHealth applications to respectively monitor asthma control and quality of life.
几种新开发的电子健康应用程序使用在线问卷来监测哮喘控制情况。哮喘控制问卷（ACQ）和哮喘生活质量问卷（AQLQ）就是两种常用的问卷。这些问卷在纸质版上已得到验证。本研究旨在通过评估ACQ和AQLQ在线版与纸质版之间的一致性来对其进行验证。
本研究纳入了来自“医院、信息通信技术、护士和全科医生支持的哮喘自我管理”（SMASHING）试验和达沃斯家庭研究中的患者（年龄在18岁及以上）。患者在2周内以随机顺序完成了ACQ和AQLQ的纸质版和荷兰语在线版。使用配对t检验、组内相关系数和布兰德-奥特曼图评估不同版本之间的一致性。
共有44名患者符合分析条件。ACQ纸质版和在线版之间的平均差异为0.04（p = 0.40），AQLQ的平均差异为0.08（p = 0.06）。ACQ的组内相关系数得分是0.94，AQLQ是0.95。
ACQ和AQLQ的在线版与纸质版显示出高度一致性，因此可以安全地用于电子健康应用程序中，分别监测哮喘控制情况和生活质量。
