Chen Wenbo, Li Hong, Chen Yuzhou, Jiang Fangyi, Wu Yang, Chen Shiyi
Department of Sports Medicine, Huashan Hospital, Shanghai, People's Republic of China.
Orthop J Sports Med. 2019 Nov 27;7(11):2325967119885314. doi: 10.1177/2325967119885314. eCollection 2019 Nov.
Bone-patellar tendon-bone (BPB) autografts and hamstring tendon (HT) autografts are 2 popular choices for anterior cruciate ligament reconstruction (ACLR). Although existing meta-analyses have explored the clinical outcomes between BPB and HT autografts, none have based their analysis on studies with just femoral suspensory fixation methods.
To evaluate and compare clinical outcomes, particularly graft failure and knee stability, of ACLR with BPB or HT autografts with suspensory femoral fixation.
Systematic review; Level of evidence, 4.
A literature search was conducted of studies reporting single-bundle ACLR with BPB autografts and HT autografts with suspensory fixation with a minimum 24-month follow-up. Graft failure rate, knee stability, and clinical outcomes were compared for BPB versus HT autografts. Knee stability was measured with the Lachman test, pivot-shift test, and KT-1000/2000 arthrometer side-to-side difference (SSD). Clinical outcomes were measured with Lysholm scores and the Tegner activity scale, as well as rate of return to preinjury sports. Donor site morbidity among included studies was reviewed. A random-effects model was used for calculations of summary estimates. Subgroup, sensitivity, and trial sequential analyses were conducted.
Five studies were included. Graft failure was seen more often in the HT group than the BPB group, and this was statistically significant ( = .03). However, the trial sequential analysis outcome indicated that the included sample size was not large enough to support a solid positive finding. The analysis showed no significant difference in SSD, Lachman test, pivot-shift test, rate of return to sports, Lysholm score, or Tegner score between groups. Subgroup analyses found no significant difference between groups.
This meta-analysis demonstrated no significant differences in knee stability and knee functional outcomes between BPB and HT autografts with suspensory fixation. More evidence is needed to prove the lower risk of failure with use of BTB autograft with suspensory fixation.
骨-髌腱-骨(BPB)自体移植物和腘绳肌腱(HT)自体移植物是前交叉韧带重建(ACLR)的两种常用选择。尽管现有的荟萃分析探讨了BPB和HT自体移植物之间的临床结果,但没有一项分析基于仅采用股骨悬吊固定方法的研究。
评估和比较采用股骨悬吊固定的BPB或HT自体移植物进行ACLR的临床结果,尤其是移植物失败和膝关节稳定性。
系统评价;证据等级,4级。
对报告采用BPB自体移植物和HT自体移植物进行单束ACLR并采用悬吊固定且随访至少24个月的研究进行文献检索。比较BPB与HT自体移植物的移植物失败率、膝关节稳定性和临床结果。采用Lachman试验、轴移试验和KT-1000/2000关节测量仪测量两侧差值(SSD)评估膝关节稳定性。采用Lysholm评分、Tegner活动量表以及伤前运动恢复率评估临床结果。对纳入研究中的供区并发症进行了综述。采用随机效应模型计算汇总估计值。进行了亚组分析、敏感性分析和试验序贯分析。
纳入5项研究。HT组移植物失败的发生率高于BPB组,且具有统计学意义(P = .03)。然而,试验序贯分析结果表明,纳入的样本量不足以支持得出确凿的阳性结果。分析显示,两组之间在SSD、Lachman试验、轴移试验、运动恢复率、Lysholm评分或Tegner评分方面无显著差异。亚组分析发现两组之间无显著差异。
这项荟萃分析表明,采用悬吊固定的BPB和HT自体移植物在膝关节稳定性和膝关节功能结果方面无显著差异。需要更多证据来证明采用悬吊固定的BTB自体移植物失败风险更低。