Liu Biyuan, Fan Zhu, Wang Zheyi, Li Man, Lu Tao
School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
School of Medicine, University of St Andrews, Scotland, UK.
Medicine (Baltimore). 2020 Jan;99(3):e18734. doi: 10.1097/MD.0000000000018734.
Non-pharmacological treatments (education, exercise, and physical therapy) are remain basic approaches to long-term management of ankylosing spondylitis (AS) patients. As an important part of non-pharmacological treatments, Health Qigong is widely used for AS treatment. We will perform the systematic review to confirm the safety and efficacy of Health Qigong for AS.
Systematical search of 6 electronic databases will be done, including English and Chinese, until December 2019. All randomized controlled trials (RCTs) involving Health Qigong in combination with conventional therapy for AS will be included. Study selection, data extraction, and validation were performed independently by 2 reviewers. RevMan (V.5.3) will be used for mata-analysis.
This systematic review will identify the safety and efficacy of Health Qigong in the treatment of AS and update evidence summaries of Health Qigong. At the end of the treatment, the primary outcome is Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) with a range of 0 to 10,and the secondary outcomes will include functional ability that measured by Bath Ankylosing Spondylitis Functional Index (BASFI), mobility measured by Bath Ankylosing Spondylitis Metrology Index (BASMI), chest expansion, night spinal pain, adverse reactions, laboratory measures such as erythrocyte sedimentation rate (ESR) and C protein response (CRP).
This study will provide evidence that whether Health Qigong can benefit patients with ankylosing spondylitis by reducing disease activity, alleviating pain to support the application of Health Qigong in the AS treatment.
CRD42019159126.
非药物治疗（教育、运动和物理治疗）仍然是强直性脊柱炎（AS）患者长期管理的基本方法。作为非药物治疗的重要组成部分，健身气功被广泛用于AS的治疗。我们将进行系统评价以证实健身气功治疗AS的安全性和有效性。
将对6个电子数据库进行系统检索，包括英文和中文数据库，检索截至2019年12月。纳入所有涉及健身气功联合传统疗法治疗AS的随机对照试验（RCT）。由2名研究者独立进行研究选择、数据提取和验证。将使用RevMan（V.5.3）进行荟萃分析。
本系统评价将确定健身气功治疗AS的安全性和有效性，并更新健身气功的证据总结。治疗结束时，主要结局指标是巴斯强直性脊柱炎疾病活动指数（BASDAI），范围为0至10，次要结局指标将包括通过巴斯强直性脊柱炎功能指数（BASFI）测量的功能能力、通过巴斯强直性脊柱炎测量指数（BASMI）测量的活动度、胸廓活动度、夜间脊柱疼痛、不良反应、实验室指标如红细胞沉降率（ESR）和C反应蛋白（CRP）。
本研究将提供证据，证明健身气功是否可通过降低疾病活动度、减轻疼痛使强直性脊柱炎患者获益，以支持健身气功在AS治疗中的应用。
CRD42019159126。
