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传统气功锻炼对强直性脊柱炎的影响:系统评价与Meta分析方案

Effects of traditional qigong exercise on ankylosing spondylitis: a protocol for systematic reviews and meta-analysis.

作者信息

Liu Wei, Fan Yihua, Wan Renhong, Zhao Longmei, Lu Hang, Liao Rongjun, Zhuang Zhining, Guo Xiaoping

机构信息

Department of Rheumatism and Immunology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China

National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China.

出版信息

BMJ Open. 2021 Apr 21;11(4):e046188. doi: 10.1136/bmjopen-2020-046188.

Abstract

INTRODUCTION

Ankylosing spondylitis (AS) is a recurrent autoimmune disease that is associated with a high disability rate, which has a profound negative impact on daily life. It has been clinically reported that traditional qigong exercise has certain therapeutic advantages in treating AS; however, this postulation is not evidence-based. Therefore, this study will aim at systematically appraising the validity and safety of traditional qigong exercise in treating AS.

METHODS AND ANALYSIS

We searched the English (PubMed, Embase, Web of Science and the Cochrane Library) and Chinese databases (China National Knowledge Infrastructure, Wan fang, VIP and Chinese biomedical database) for relevant information. Additionally, the Baidu Academic and Google Academic databases were manually searched to mine relevant information. Randomised controlled clinical trials of traditional qigong exercise in treating AS were searched from the establishment of the database to September 2020. Quality articles were extracted and independently evaluated by two researchers before inclusion in this study. Meta-analysis of the included articles was performed using the RevMan V.5.3 software.

ETHICS AND DISSEMINATION

This study will not involve primary data collection, and formal ethics approval will, therefore, not be required. We aim to publish this systematic review in a peer-reviewed journal.

TRIAL REGISTRATION NUMBER

CRD42020207057.

摘要

引言

强直性脊柱炎(AS)是一种复发性自身免疫性疾病,致残率高,对日常生活有深远的负面影响。临床报道称,传统气功锻炼在治疗AS方面具有一定的治疗优势;然而,这一假设缺乏循证依据。因此,本研究旨在系统评价传统气功锻炼治疗AS的有效性和安全性。

方法与分析

我们检索了英文数据库(PubMed、Embase、Web of Science和Cochrane图书馆)和中文数据库(中国知网、万方、维普和中国生物医学数据库)以获取相关信息。此外,还手动检索了百度学术和谷歌学术数据库以挖掘相关信息。检索从数据库建立至2020年9月期间关于传统气功锻炼治疗AS的随机对照临床试验。提取高质量文章,并由两名研究人员在纳入本研究之前进行独立评估。使用RevMan V.5.3软件对纳入的文章进行荟萃分析。

伦理与传播

本研究不涉及原始数据收集,因此无需正式伦理批准。我们旨在将本系统评价发表在同行评审期刊上。

试验注册号

CRD42020207057。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b42f/8061814/3d60141352af/bmjopen-2020-046188f01.jpg

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