Rehabilitation Medicine College, Henan University of Chinese Medicine, 156 Jinshui East Road, Zhengzhou, Henan, China.
School of Traditional Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou, Henan, China.
J Orthop Surg Res. 2024 Sep 28;19(1):586. doi: 10.1186/s13018-024-05072-5.
To evaluate the efficacy and safety of mind-body exercise (MBE) interventions, including Tai Chi, Yoga, Pilates, and Qigong, in patients with axial spondyloarthritis (axSpA), a systematic review and meta-analysis was conducted.
Eight electronic databases were searched from their inception to May 2024. RevMan 5.4 and Stata 16.0 software were used for statistical analysis. Outcome measures included Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Visual Analog Scale (VAS), Bath Ankylosing Spondylitis Metrology Index (BASMI), Ankylosing Spondylitis Quality of Life (ASQoL) Scale, and adverse events. The methodological quality of the included studies was evaluated using the Cochrane risk of bias (RoB) tool (2.0). The certainty of evidence for each outcome was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) criteria.
Of the 330 studies retrieved, 15 studies satisfied the criteria for meta-analysis. Compared with the controls, MBE interventions significantly improved physical function (measured by BASFI, MD = -0.76, 95% CI: -1.01 to -0.50, P < 0.00001), disease activity (measured by BASDAI, MD = -0.76, 95% CI: -0.94 to -0.57, P < 0.00001), pain intensity (measured by VAS, MD = -0.89, 95% CI: -1.21 to -0.57, P < 0.00001), spinal mobility (measured by BASMI, MD = -0.44, 95% CI: -0.70 to -0.19, P = 0.0006), and quality of life (measured by ASQoL, MD = -2.14, 95% CI: -3.54 to -0.75, P = 0.003). Subgroup analyses revealed that Tai Chi appeared to demonstrate a more pronounced effect on pain reduction when compared to Qigong (test for subgroup difference: P = 0.005). The quality of evidence for these outcomes was estimated as moderate to low. Additionally, no serious adverse events related to MBE were identified among the included studies.
Overall, MBE may be a promising non-pharmacological treatment to improve physical function, disease activity, pain intensity, spinal mobility, and quality of life in patients with axSpA. To enhance the certainty of the evidence, additional rigorous studies are needed to verify these findings.
评估身心锻炼（MBE）干预措施（包括太极拳、瑜伽、普拉提和气功）在轴性脊柱关节炎（axSpA）患者中的疗效和安全性，为此进行了系统评价和荟萃分析。
从建库到 2024 年 5 月，检索了 8 个电子数据库。使用 RevMan 5.4 和 Stata 16.0 软件进行统计分析。结局指标包括 Bath 强直性脊柱炎功能指数（BASFI）、Bath 强直性脊柱炎疾病活动指数（BASDAI）、视觉模拟量表（VAS）、Bath 强直性脊柱炎衡量指数（BASMI）、强直性脊柱炎生活质量量表（ASQoL）和不良事件。使用 Cochrane 偏倚风险（RoB）工具（2.0 版）评估纳入研究的方法学质量。使用 Grading of Recommendations Assessment, Development, and Evaluation（GRADE）标准评估每个结局的证据确定性。
在检索到的 330 项研究中，有 15 项研究符合荟萃分析的标准。与对照组相比，MBE 干预措施显著改善了身体功能（用 BASFI 衡量，MD=-0.76，95%CI：-1.01 至-0.50，P<0.00001）、疾病活动度（用 BASDAI 衡量，MD=-0.76，95%CI：-0.94 至-0.57，P<0.00001）、疼痛强度（用 VAS 衡量，MD=-0.89，95%CI：-1.21 至-0.57，P<0.00001）、脊柱活动度（用 BASMI 衡量，MD=-0.44，95%CI：-0.70 至-0.19，P=0.0006）和生活质量（用 ASQoL 衡量，MD=-2.14，95%CI：-3.54 至-0.75，P=0.003）。亚组分析显示，与气功相比，太极拳似乎在减轻疼痛方面显示出更显著的效果（检验亚组差异：P=0.005）。这些结局的证据质量估计为中等到低。此外，纳入的研究中未发现与 MBE 相关的严重不良事件。
总体而言，MBE 可能是一种有前途的非药物治疗方法，可以改善 axSpA 患者的身体功能、疾病活动度、疼痛强度、脊柱活动度和生活质量。为了提高证据的确定性，需要进行更多严格的研究来验证这些发现。
