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医院相关疫情的一个动因:我们需要牢记哪些具有挑战性的问题?

, an Agent of Hospital-Associated Outbreaks: Which Challenging Issues Do We Need to Have in Mind?

作者信息

Sabino Raquel, Veríssimo Cristina, Pereira Álvaro Ayres, Antunes Francisco

机构信息

Reference Unit for Parasitic and Fungal Infections, Infectious Diseases Department, National Institute of Health Dr. Ricardo Jorge, Avenida Padre Cruz, 1649-016 Lisbon, Portugal.

Instituto de Saúde Ambiental, Faculdade de Medicina da Universidade de Lisboa, Av. Prof. Egas Moniz, Ed. Egas Moniz, 1649-028 Lisboa, Portugal.

出版信息

Microorganisms. 2020 Jan 28;8(2):181. doi: 10.3390/microorganisms8020181.

DOI:10.3390/microorganisms8020181
PMID:32012865
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7074697/
Abstract

The emergence of is considered as one of the most serious problems associated with nosocomial transmission and with infection control practices in hospital environment. This multidrug resistant species is rapidly spreading worldwide, with several described outbreaks. Until now, this species has been isolated from different hospital surfaces, where it can survive for long periods. There are multiple unanswered questions regarding , such as prevalence in population, environmental contamination, effectiveness of infection prevention and control, and impact on patient mortality. In order to understand how it spreads and discover possible reservoirs, it is essential to know the ecology, natural environment, and distribution of this species. It is also important to explore possible reasons to this recent emergence, namely the environmental presence of azoles or the possible effect of climate change on this sudden emergence. This review aims to discuss some of the most challenging issues that we need to have in mind in the management of and to raise the awareness to its presence in specific indoor environments as hospital settings.

摘要

[物种名称]的出现被认为是与医院感染传播及医院环境感染控制措施相关的最严重问题之一。这种多重耐药菌正在全球迅速传播,已有多起暴发事件的报道。到目前为止,该物种已从医院的不同表面分离出来,并且能够在这些表面长期存活。关于[物种名称]仍有多个未解决的问题,例如在人群中的流行情况、环境污染、感染预防与控制的有效性以及对患者死亡率的影响。为了了解其传播方式并发现可能的储存宿主,有必要了解该物种的生态学、自然环境和分布情况。探究其近期出现的可能原因也很重要,即环境中唑类药物的存在或气候变化对其突然出现可能产生的影响。本综述旨在讨论在[物种名称]管理中需要牢记的一些最具挑战性的问题,并提高人们对其在医院等特定室内环境中存在的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee63/7074697/babac5346b49/microorganisms-08-00181-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee63/7074697/babac5346b49/microorganisms-08-00181-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee63/7074697/babac5346b49/microorganisms-08-00181-g001.jpg

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