Department of Foundations of Medicine, New York University Long Island School of Medicine, Mineola, New York, NY 11501, USA.
Diabetes and Obesity Research Center, NYU Winthrop Hospital, Mineola, New York, NY 11501, USA.
Int J Mol Sci. 2020 Jan 28;21(3):831. doi: 10.3390/ijms21030831.
The goal of this review was to seek a better understanding of the function and differential expression of circadian clock genes during the reproductive process. Through a discussion of how the circadian clock is involved in these steps, the identification of new clinical targets for sleep disorder-related diseases, such as reproductive failure, will be elucidated. Here, we focus on recent research findings regarding circadian clock regulation within the reproductive system, shedding new light on circadian rhythm-related problems in women. Discussions on the roles that circadian clock plays in these reproductive processes will help identify new clinical targets for such sleep disorder-related diseases.
本综述的目的是更好地了解生物钟基因在生殖过程中的功能和差异表达。通过讨论生物钟如何参与这些步骤,可以阐明与睡眠障碍相关疾病(如生殖失败)相关的新的临床靶点。在这里,我们重点关注生殖系统中生物钟调节的最新研究发现,为女性的昼夜节律相关问题提供新的视角。讨论生物钟在这些生殖过程中的作用将有助于确定与睡眠障碍相关疾病相关的新的临床靶点。