Fang Weiwei, Zheng Cuiling, Wang Li, Cui Wei
Clin Lab. 2020 Jan 1;66(1). doi: 10.7754/Clin.Lab.2019.190616.
Blood status is closely related to the hemoglobin test results in clinical laboratory. This paper discusses a case of which hemoglobin test results were not interfered by the "milky" blood status.
Complete Blood Count with Differential (CBC + Diff) was detected for these two specimens with a Sysmex XN-9000.
The results of red cell indices for patient I were as follows: red blood cell count (RBC), 5.10 x 1012/L; hematocrit (HCT), 0.455 L/L; hemoglobin (HGB), 167 g/L; mean corpuscular hemoglobin concentration (MCHC), 367 g/L, and triglycerides (TG), 1.59 mmol/L. There was no "turbidity" warning message. However, there was a "turbidity" warning message for patient II and his red cell indices were RBC, 4.74 x 1012/L; HCT, 0.492 L/L; HGB, 182 g/L; MCHC, 370 g/L, and TG, 12.98 mmol/L. After the plasma exchange, there was no "turbidity" warning message for patient I and his red cell indices were RBC, 4.83 x 1012/L; HCT, 0.444 L/L; HGB, 164 g/L; MCHC, 369 g/L which were consistent with the results before the plasma exchange. For patient II, the "turbidity" warning message disappeared and his results were RBC, 3.87 x 1012/L; HCT, 0.398 L/L; HGB, 135 g/L; MCHC, 339 g/L.
Our case provided an explanation of the normal hemoglobin detection results in the visible lipemic specimen for the first time.
临床实验室中血液状态与血红蛋白检测结果密切相关。本文讨论了一例血红蛋白检测结果未受“乳糜样”血液状态干扰的病例。
使用Sysmex XN - 9000对这两份标本进行全血细胞计数及分类（CBC + Diff）检测。
患者I的红细胞指数结果如下：红细胞计数（RBC），5.10×10¹²/L；血细胞比容（HCT），0.455 L/L；血红蛋白（HGB），167 g/L；平均红细胞血红蛋白浓度（MCHC），367 g/L，甘油三酯（TG），1.59 mmol/L。无“浑浊”警告信息。然而，患者II出现了“浑浊”警告信息，其红细胞指数为：RBC，4.74×10¹²/L；HCT，0.492 L/L；HGB，182 g/L；MCHC，370 g/L，TG，12.98 mmol/L。血浆置换后，患者I无“浑浊”警告信息，其红细胞指数为：RBC，4.83×10¹²/L；HCT，0.444 L/L；HGB，164 g/L；MCHC，369 g/L，与血浆置换前结果一致。对于患者II，“浑浊”警告信息消失，其结果为：RBC，3.87×10¹²/L；HCT，0.398 L/L；HGB，135 g/L；MCHC，339 g/L。
我们的病例首次对可见脂血标本中血红蛋白检测结果正常提供了解释。
