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新发皮肌炎患者的肠系膜脂膜炎。

Mesenteric panniculitis in a patient with new onset dermatomyositis.

作者信息

Bansal Pankaj, Gilbert Emily L, Pereira Rodrigo Otavio Lami, Virata Andrew R

机构信息

Rheumatology, Mayo Clinic Health System, Eau Claire, Wisconsin, USA

Internal Medicine, Mayo Clinic Hospital Jacksonville, Jacksonville, Florida, USA.

出版信息

BMJ Case Rep. 2020 Feb 2;13(1):e232183. doi: 10.1136/bcr-2019-232183.

DOI:10.1136/bcr-2019-232183
PMID:32014990
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7021128/
Abstract

Mesenteric panniculitis (MP), part of the spectrum of sclerosing mesenteritis, is an often asymptomatic disorder that is characterised by chronic inflammation of abdominal mesentery. We present a case of an 83-year-old woman who presented with proximal muscle weakness and erythematous, photosensitive rash of the face and upper torso and was subsequently diagnosed with dermatomyositis based on skin biopsy, electromyography and muscle biopsy. She had radiographic evidence of panniculitis on CT scan of the abdomen and pelvis for malignancy surveillance, which improved on serial CT scan 3 months after beginning treatment for her underlying dermatomyositis with prednisone and mycophenolate mofetil. Our case highlights that MP can be associated with underlying autoimmune disease. Connective tissue disease could be considered in the differential of MP when other etiologies such as surgery, trauma and malignancy are ruled out.

摘要

肠系膜脂膜炎(MP)是硬化性肠系膜炎症谱的一部分,是一种通常无症状的疾病,其特征为腹部肠系膜的慢性炎症。我们报告一例83岁女性,她出现近端肌无力以及面部和上半身的红斑性光敏皮疹,随后根据皮肤活检、肌电图和肌肉活检被诊断为皮肌炎。她因恶性肿瘤监测进行腹部和骨盆CT扫描时有脂膜炎的影像学证据,在开始使用泼尼松和霉酚酸酯治疗其潜在皮肌炎3个月后的系列CT扫描中情况有所改善。我们的病例强调MP可能与潜在的自身免疫性疾病有关。当排除手术、创伤和恶性肿瘤等其他病因时,结缔组织病可被纳入MP的鉴别诊断中。

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引用本文的文献

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Panniculitis in dermatomyositis: A systematic review of the clinicopathologic features.皮肌炎中的脂膜炎:临床病理特征的系统评价
JAAD Int. 2024 Mar 22;18:50-61. doi: 10.1016/j.jdin.2024.03.004. eCollection 2025 Feb.

本文引用的文献

1
Sclerosing mesenteritis: a systematic review of 192 cases.硬化性肠系膜脂膜炎:192例病例的系统评价
Clin J Gastroenterol. 2017 Apr;10(2):103-111. doi: 10.1007/s12328-017-0716-5. Epub 2017 Feb 14.
2
Treatment options for spontaneous and postoperative sclerosing mesenteritis.自发性和术后硬化性肠系膜炎症的治疗选择。
World J Gastrointest Surg. 2016 Nov 27;8(11):761-765. doi: 10.4240/wjgs.v8.i11.761.
3
Mesenteric Panniculitis (MP) in CT - A Predictor of Malignancy?CT 检查中的肠系膜脂膜炎(MP)——是恶性肿瘤的预测指标吗?
Rofo. 2016 Oct;188(10):926-32. doi: 10.1055/s-0042-110100. Epub 2016 Aug 16.
4
Cohort study of mesenteric panniculitis and its relationship to malignancy.肠系膜脂膜炎的队列研究及其与恶性肿瘤的关系。
Br J Surg. 2016 Nov;103(12):1727-1730. doi: 10.1002/bjs.10229. Epub 2016 Aug 12.
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Malignancy and mesenteric panniculitis.恶性肿瘤与肠系膜脂膜炎。
Colorectal Dis. 2016 Apr;18(4):372-7. doi: 10.1111/codi.13154.
6
Limited systemic sclerosis initially presenting with mesenteric panniculitis.局限性系统性硬化症最初表现为肠系膜脂膜炎。
BMJ Case Rep. 2014 Oct 17;2014:bcr2014206961. doi: 10.1136/bcr-2014-206961.
7
Mesenteric panniculitis. Part 2: prevalence and natural course: MDCT prospective study.肠系膜脂膜炎。第2部分:患病率和自然病程:MDCT前瞻性研究。
JBR-BTR. 2011 Sep-Oct;94(5):241-6. doi: 10.5334/jbr-btr.659.
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Sclerosing Mesenteritis: Diverse clinical presentations and dissimilar treatment options. A case series and review of the literature.硬化性肠系膜脂膜炎:多样的临床表现及不同的治疗选择。病例系列报道及文献综述
Int Arch Med. 2011 Jun 2;4:17. doi: 10.1186/1755-7682-4-17.
9
A case of sclerosing mesenteritis with rheumatoid arthritis.一例伴有类风湿关节炎的硬化性肠系膜炎症。
South Med J. 2010 Jan;103(1):96-7. doi: 10.1097/SMJ.0b013e3181c47b7c.
10
Sclerosing mesenteritis: clinical features, treatment, and outcome in ninety-two patients.硬化性肠系膜脂膜炎:92例患者的临床特征、治疗及预后
Clin Gastroenterol Hepatol. 2007 May;5(5):589-96; quiz 523-4. doi: 10.1016/j.cgh.2007.02.032.