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微打磨及微打磨后应用酪蛋白磷酸肽-无定形氟化钙磷酸盐对磨牙区恒前牙矿化不全患牙美学效果的对比评估

Comparative Evaluation of Esthetics after Microabrasion and Microabrasion followed by Casein Phosphopeptide-Amorphous Calcium Fluoride Phosphate on Molar Incisor Hypomineralization-Affected Incisors.

作者信息

Bhandari Ranu, Thakur Seema, Singhal Parul, Chauhan Deepak, Jayam Cheranjeevi, Jain Teerthesh

机构信息

Department of Pedodontics, H.P. Government Dental College and Hospital, Shimla, Himachal Pradesh, India.

School of Dental Medicine, University of Colorado, Denver, Colorado, USA.

出版信息

Contemp Clin Dent. 2019 Jan-Mar;10(1):9-15. doi: 10.4103/ccd.ccd_852_17.

DOI:10.4103/ccd.ccd_852_17
PMID:32015635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6975009/
Abstract

BACKGROUND

Molar incisor hypomineralization (MIH) is an esthetic setback for the patient as well as for the dentist, treatment options for MIH includes minimally invasive techniques like microabrasion which has a limited literature of its effect. Furthermore, the effect of remineralizing such as casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) agent on MIH-affected teeth is minimally studied.

AIM

Comparative evaluation of the esthetic after microabrasion and microabrasion followed by Tooth Mousse Plus on hypomineralized incisors of MIH-affected patients.

SETTINGS AND DESIGN

The study was a randomized clinical trial.

MATERIALS AND METHODS

The study comprised Grade I MIH patients in the age strata of 7-16 years having lesions on incisors. As per inclusion criteria, 46 lesions were divided into two groups of microabrasion and microabrasion followed by CPP-amorphous calcium fluoride phosphate (ACFP). Photographs were obtained before treatment, just after treatment, and 6 months after treatment. The photographic evaluation was done using the CIE Lab* scoring method.

STATISTICAL ANALYSIS USED

ANOVA and Tukey's test were applied to compare the difference in lightness ΔL and total color change ΔE of these two groups.

RESULTS

In microabrasion group, the overall change in ΔL of white tooth discoloration came -0.9 standard deviation (SD) 7.3. In microabrasion followed by CPP-ACFP group, statistically significant difference was found between both these groups with value of ≤ 0.001.

CONCLUSIONS

Microabrasion followed by the remineralizing agent can improve the esthetics of white tooth discoloration with time.

摘要

背景

磨牙症性切牙低矿化(MIH)对患者和牙医来说都是一种美学上的挫折,MIH的治疗选择包括微磨除等微创技术,但其效果的相关文献有限。此外,酪蛋白磷酸肽 - 无定形磷酸钙(CPP - ACP)等再矿化剂对受MIH影响牙齿的作用研究极少。

目的

比较微磨除以及微磨除后使用牙齿护理霜加强型(Tooth Mousse Plus)对MIH患者低矿化切牙美学效果的影响。

设置与设计

该研究为随机临床试验。

材料与方法

该研究纳入了年龄在7 - 16岁、切牙有病变的I级MIH患者。根据纳入标准,将46处病变分为微磨除组和微磨除后使用CPP - 无定形氟化磷酸钙(ACFP)组。在治疗前、治疗后即刻以及治疗后6个月拍摄照片。使用CIE Lab*评分法进行照片评估。

所用统计分析方法

应用方差分析(ANOVA)和Tukey检验来比较两组的明度变化ΔL和总颜色变化ΔE的差异。

结果

在微磨除组中,白色牙齿变色的ΔL总体变化为 -0.9标准差(SD)7.3。在微磨除后使用CPP - ACFP组中,两组之间发现有统计学显著差异,P值≤0.001。

结论

微磨除后使用再矿化剂可随时间改善白色牙齿变色的美学效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/6975009/7ce5a73ce287/CCD-10-9-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/6975009/965317fa94e3/CCD-10-9-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/6975009/96ff5f6c1f13/CCD-10-9-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/6975009/d35749de5121/CCD-10-9-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/6975009/9d1751973d67/CCD-10-9-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/6975009/7ce5a73ce287/CCD-10-9-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/6975009/965317fa94e3/CCD-10-9-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/6975009/96ff5f6c1f13/CCD-10-9-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/6975009/d35749de5121/CCD-10-9-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/6975009/9d1751973d67/CCD-10-9-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d9a/6975009/7ce5a73ce287/CCD-10-9-g005.jpg

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本文引用的文献

1
Tooth colour and whiteness: A review.牙齿颜色和美白:综述。
J Dent. 2017 Dec;67S:S3-S10. doi: 10.1016/j.jdent.2017.09.006. Epub 2017 Sep 18.
2
Prevention and Treatment of White Spot Lesions During and After Treatment with Fixed Orthodontic Appliances: a Systematic Literature Review.固定正畸矫治器治疗期间及治疗后白斑病变的防治:一项系统文献综述
J Oral Maxillofac Res. 2016 Jun 30;7(2):e1. doi: 10.5037/jomr.2016.7201. eCollection 2016 Apr-Jun.
3
Microabrasion in tooth enamel discoloration defects: three cases with long-term follow-ups.
使用树脂渗透法治疗受磨牙-切牙矿化不全(MIH)影响的恒切牙:一项试点研究。
Eur Arch Paediatr Dent. 2024 Feb;25(1):105-116. doi: 10.1007/s40368-024-00861-2. Epub 2024 Jan 29.
4
Update of the molar incisor hypomineralization: Würzburg concept.《低龄儿童恒牙龋、中龋和猖獗龋:沃茨堡概念》更新。
Eur Arch Paediatr Dent. 2023 Dec;24(6):807-813. doi: 10.1007/s40368-023-00848-5. Epub 2023 Oct 19.
5
Contemporary Understanding of the Etiology and Management of Molar Incisor Hypomineralization: A Literature Review.磨牙切牙矿化不全病因及管理的当代认识:文献综述
Dent J (Basel). 2023 Jun 23;11(7):157. doi: 10.3390/dj11070157.
6
Management of Hypoplastic or Hypomineralized Defects with Resin Infiltration at Pediatric Ages: Systematic Review.儿童时期树脂渗透治疗牙釉质发育不全或矿化不全缺陷的管理:系统评价。
Int J Environ Res Public Health. 2023 Mar 15;20(6):5201. doi: 10.3390/ijerph20065201.
7
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8
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9
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Eur Arch Paediatr Dent. 2022 Feb;23(1):3-21. doi: 10.1007/s40368-021-00668-5. Epub 2021 Oct 20.
10
Color assessment of resin composite by using cellphone images compared with a spectrophotometer.通过手机图像与分光光度计对树脂复合材料进行颜色评估。
Restor Dent Endod. 2021 Apr 5;46(2):e23. doi: 10.5395/rde.2021.46.e23. eCollection 2021 May.
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4
Esthetic management of developmental enamel opacities in young permanent maxillary incisors with two microabrasion techniques--a split mouth study.两种微磨耗技术用于年轻恒牙上颌切牙发育性釉质混浊的美学处理——一项双盲研究
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5
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6
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7
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J Dent. 2013 Nov;41 Suppl 5:e28-34. doi: 10.1016/j.jdent.2013.04.003. Epub 2013 Apr 11.
8
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J Conserv Dent. 2012 Jan;15(1):61-7. doi: 10.4103/0972-0707.92609.
9
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10
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