Gupta Ruchi, Prakash Vijay
Department of Conservative Dentistry and Department of Prosthodontics, I.T.S. Centre for Dental Studies & Research Muradnagar, Ghaziabad, UP, India.
Oral Health Prev Dent. 2011;9(2):151-65.
In addition to regular professional oral hygiene visits and the application of appropriate preventive medications, successful preventive strategies involve oral health promotion, patient education and patient compliance. The Casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) complex has been shown to remineralise tooth surfaces in situ when delivered in oral care products. This complex has a unique ability to deliver bio-available calcium and phosphate when they are needed most. The effectiveness of casein derivatives, specifically CCP-ACP, in caries prevention and lesion reversal has been supported by many controlled clinical studies. This review summarises the research on Casein phosphopeptide-amorphous calcium phosphate complex and provides information related to its benefit in dentistry. Further research is required to provide a scientifically supported recommendation for other clinical applications.
除了定期进行专业口腔卫生检查和应用适当的预防性药物外，成功的预防策略还包括口腔健康促进、患者教育和患者依从性。酪蛋白磷酸肽-无定形磷酸钙（CPP-ACP）复合物在口腔护理产品中使用时，已被证明能在原位使牙齿表面再矿化。这种复合物具有独特的能力，能在最需要的时候提供生物可利用的钙和磷。许多对照临床研究都证实了酪蛋白衍生物，特别是CCP-ACP在预防龋齿和病变逆转方面的有效性。本综述总结了关于酪蛋白磷酸肽-无定形磷酸钙复合物的研究，并提供了与其在牙科领域的益处相关的信息。还需要进一步的研究，以便为其他临床应用提供科学支持的建议。
