Arangannal Ponnudurai, Muthiah Gomagal, Jeevarathan J, Sankar P
Department of Paedodontics and Preventive Dentistry, Sree Balaji Dental College and Hospital, Chennai, Tamil Nadu, India.
Contemp Clin Dent. 2019 Jan-Mar;10(1):31-35. doi: 10.4103/ccd.ccd_124_18.
The aim of this study is to evaluate the clinical and radiographic success of endodontic treatment of nonvital primary teeth using lesion sterilization and tissue repair (LSTR) therapy.
A sample size of 40 primary molars from 34 children of 3-10 years of age were selected for the study. Nonvital primary molars were treated using LSTR technique with a combination of antibacterial drugs comprising ciprofloxacin, metronidazole, and doxycycline with propylene glycol as vehicle. The procedure was completed in a single appointment. Only analgesics were prescribed postoperatively. Postoperative evaluation was done after 1, 3, 6, and 12 months.
Clinical signs and symptoms got resolved in the 1-month follow-up itself and continued in the subsequent visits. Radiographic evaluation showed a gradual improvement in success rates through the 12-month follow-up period.
LSTR technique can be considered as an alternative treatment option for nonvital primary teeth avoiding a course of systemic antibiotics to the children. Doxycycline can be used in the drug combination instead of minocycline which also gives higher clinical and radiographic success.
本研究旨在评估采用病灶消毒和组织修复（LSTR）疗法对无活力乳牙进行根管治疗的临床和影像学成功率。
选取34名3至10岁儿童的40颗乳牙作为研究样本。采用LSTR技术，以环丙沙星、甲硝唑和强力霉素组成的抗菌药物组合并以丙二醇作为载体对无活力乳牙进行治疗。该操作在一次就诊时完成。术后仅开了镇痛药。术后在1、3、6和12个月进行评估。
临床体征和症状在1个月的随访时就已缓解，并在随后的随访中持续改善。影像学评估显示，在12个月的随访期内成功率逐渐提高。
LSTR技术可被视为无活力乳牙的一种替代治疗选择，避免给儿童使用全身性抗生素疗程。强力霉素可用于药物组合中替代米诺环素，其临床和影像学成功率也较高。
