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绿茶漱口水和绿茶凝胶对12 - 18岁青少年唾液及菌落计数影响的疗效比较评估:一项随机临床试验

Comparative Evaluation of Efficacy of Green Tea Mouth Rinse and Green Tea Gel on the Salivary and Colony Count in 12-18-year-old Teenagers: A Randomized Clinical Trial.

作者信息

Ahmadi Maryam Haji, Sarrami Leila, Yegdaneh Afsaaneh, Homayoni Alireza, Bakhtiyari Zohreh, Danaeifar Nasrin, Akhlaghi Najmeh

机构信息

Department of Pediatric Dentistry, Dental Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

General Dentist, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

Contemp Clin Dent. 2019 Jan-Mar;10(1):81-85. doi: 10.4103/ccd.ccd_368_18.

Abstract

AIMS

Green tea is an antibacterial agent with no significant side effect. This feature makes green tea safe for children to use. The purpose of this study was to compare the effectiveness of green tea gel and mouth rinse on salivary level of and of teenagers aged 12-18 years.

SUBJECTS AND METHODS

In this randomized controlled clinical trial study, 30 children aged 12-18 years were included in the study according to the inclusion criteria and were randomly divided into two groups. Participants in mouth rinse group were asked to rinse their mouth with 0.5% green tea mouthwash twice a day for 2 weeks. In the gel group, participants were requested to brush their teeth with 0.5% green tea gel twice a day for 2 weeks. After 4 weeks of washout period, mouthwash group applied the gel and the gel group rinsed the mouthwash for 2 weeks and with the same instruction as mentioned. Colony count of and was determined before and after intervention and data were analyzed using test.

RESULTS

According to the independent test, there was no significant difference in the salivary levels of S. mutans before and after intervention regarding age and gender ( = 0.33). Results from paired -test showed significant decrease in the mean count of and colonies in both groups before and after intervention ( < 0.001).

CONCLUSIONS

Green tea gel and mouthwash contribute to a significant reduction of salivary levels of and colonies, with a greater effect of mouthwash than the green tea gel, which was not statistically significant.

摘要

目的

绿茶是一种抗菌剂,且副作用不显著。这一特性使绿茶对儿童使用较为安全。本研究的目的是比较绿茶凝胶和漱口水对12至18岁青少年唾液中变形链球菌和远缘链球菌水平的效果。

受试者与方法

在这项随机对照临床试验研究中,30名12至18岁的儿童根据纳入标准被纳入研究,并随机分为两组。漱口水组的参与者被要求每天用0.5%的绿茶漱口水漱口两次,持续2周。在凝胶组中,参与者被要求每天用0.5%的绿茶凝胶刷牙两次,持续2周。在4周的洗脱期后,漱口水组使用凝胶,凝胶组使用漱口水,持续2周,使用相同的说明。在干预前后测定变形链球菌和远缘链球菌的菌落计数,并使用检验分析数据。

结果

根据独立检验,干预前后唾液中变形链球菌水平在年龄和性别方面无显著差异(P = 0.33)。配对t检验结果显示,两组干预前后变形链球菌和远缘链球菌菌落的平均计数均显著下降(P < 0.001)。

结论

绿茶凝胶和漱口水有助于显著降低唾液中变形链球菌和远缘链球菌菌落的水平,漱口水的效果比绿茶凝胶更大,但无统计学意义。

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本文引用的文献

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A randomized trial on the inhibitory effect of chewing gum containing tea polyphenol on caries.
J Clin Pediatr Dent. 2013 Fall;38(1):67-70. doi: 10.17796/jcpd.38.1.c0tm02w572488064.
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