三匹年轻纯种马的骨关节感染由一种新型革兰氏阴性球杆菌引起。
Osteoarticular Infection in Three Young Thoroughbred Horses Caused by a Novel Gram Negative Cocco-Bacillus.
作者信息
Hudson Bernard J, Chicken Catherine, Blishen Anna, Todhunter Kristen H, Begg Angela P, Chan Leonie, Karagiannis Thomas, Raymond Benjamin, Bogema Daniel, Adkins Angus R, O'Sullivan Christopher B, O'Rourke Brendon A, Roy Chowdhury Piklu, Djordjevic Steven P, Charles Ian G, Edgar Andrew, Mitsakos Katerina
机构信息
NSW Health Pathology, Department of Microbiology & Infectious Diseases, Royal North Shore Hospital, St Leonards, Sydney, New South Wales 2065, Australia.
Scone Equine Hospital, 106 Liverpool Street, Scone, New South Wales 2337, Australia.
出版信息
Case Rep Vet Med. 2020 Jan 19;2020:9785861. doi: 10.1155/2020/9785861. eCollection 2020.
We describe three cases of osteoarticular infection (OAI) in young thoroughbred horses in which the causative organism was identified by MALDI-TOF as . The pattern of OAI resembled that reported with infection in humans. Analysis by 16S rRNA PCR enabled construction of a phylogenetic tree that placed the isolates closer to and , rather than . Average nucleotide identity (ANI) comparison between the new isolate and and however revealed low probability that the new isolate belonged to either of these species. This preliminary analysis suggests the organism isolated is a previously unrecognised species.
我们描述了三例年轻纯种马的骨关节炎感染（OAI）病例，其中通过基质辅助激光解吸电离飞行时间质谱（MALDI-TOF）鉴定出致病生物体为 。OAI的模式与人类 感染报告的模式相似。通过16S rRNA聚合酶链反应（PCR）分析构建了系统发育树，该树将分离株置于更接近 和 ，而非 的位置。然而，新分离株与 和 的平均核苷酸同一性（ANI）比较显示，新分离株属于这两个物种中任何一个的可能性较低。这项初步分析表明，分离出的生物体是一个以前未被识别的物种。
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