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本文引用的文献

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Cannabis Cannabinoid Res. 2021 Feb 12;6(1):74-76. doi: 10.1089/can.2019.0056. eCollection 2021.
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Current state of evidence of cannabis utilization for treatment of autism spectrum disorders.大麻在自闭症谱系障碍治疗中的应用证据现状。
BMC Psychiatry. 2019 Oct 29;19(1):328. doi: 10.1186/s12888-019-2259-4.
3
Oral Cannabidiol Use in Children With Autism Spectrum Disorder to Treat Related Symptoms and Co-morbidities.口服大麻二酚用于治疗自闭症谱系障碍儿童的相关症状及共病。
Front Pharmacol. 2019 Jan 9;9:1521. doi: 10.3389/fphar.2018.01521. eCollection 2018.
4
Ethical Implications for Providers Regarding Cannabis Use in Children With Autism Spectrum Disorders.医疗机构在儿童自闭症谱系障碍中使用大麻的伦理问题。
Pediatrics. 2019 Feb;143(2). doi: 10.1542/peds.2018-0558. Epub 2019 Jan 4.
5
Brief Report: Cannabidiol-Rich Cannabis in Children with Autism Spectrum Disorder and Severe Behavioral Problems-A Retrospective Feasibility Study.简要报告:富含大麻二酚的大麻在自闭症谱系障碍和严重行为问题儿童中的应用——一项回顾性可行性研究。
J Autism Dev Disord. 2019 Mar;49(3):1284-1288. doi: 10.1007/s10803-018-3808-2.
6
Effects of prenatal marijuana exposure on neuropsychological outcomes in children aged 1-11 years: A systematic review.孕期暴露于大麻对1至11岁儿童神经心理结局的影响:一项系统综述。
Paediatr Perinat Epidemiol. 2018 Nov;32(6):512-532. doi: 10.1111/ppe.12505. Epub 2018 Oct 18.
7
Prevalence of Fetal Alcohol Spectrum Disorders in 4 US Communities.美国4个社区胎儿酒精谱系障碍的患病率
JAMA. 2018 Feb 6;319(5):474-482. doi: 10.1001/jama.2017.21896.
8
Pharmacotherapy in Psychiatric Disorders of Children: Current Evidence and Trends.儿童精神疾病的药物治疗:当前证据与趋势
Pharmacopsychiatry. 2016 Nov;49(6):219-225. doi: 10.1055/s-0042-117644. Epub 2016 Oct 13.
9
What Happens When Children with Fetal Alcohol Spectrum Disorders Become Adults?患有胎儿酒精谱系障碍的儿童成年后会怎样?
Curr Dev Disord Rep. 2015 Sep;2(3):219-227. doi: 10.1007/s40474-015-0053-7. Epub 2015 Jun 24.
10
Marijuana use in pregnancy and lactation: a review of the evidence.孕期及哺乳期使用大麻:证据综述
Am J Obstet Gynecol. 2015 Dec;213(6):761-78. doi: 10.1016/j.ajog.2015.05.025. Epub 2015 May 15.

大麻在儿童和孕妇中的药用情况。

Medicinal Use of Cannabis in Children and Pregnant Women.

作者信息

Koren Gideon, Cohen Rana

机构信息

Adelson Faculty of Medicine, Clinical Pharmacology Program, Ariel University, Ariel, Israel.

Motherisk Israel Program, Yitzhak Shamir Medical Center, Be'er Ya'akov, Israel.

出版信息

Rambam Maimonides Med J. 2020 Jan 30;11(1):1-5. doi: 10.5041/RMMJ.10382.

DOI:10.5041/RMMJ.10382
PMID:32017681
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7000159/
Abstract

The increasing medicinal use of cannabis during recent years has largely overlooked children and pregnant women due to litigious and ethical concerns. However, over the last few years medicine has observed increasing numbers of children treated with cannabis for autism spectrum disorder (ASD) and fetal alcohol spectrum disorder (FASD), and pregnant women treated for hyperemesis gravidarum (HG). This review provides an account of major findings discovered through this research. Specifically, cannabis may offer therapeutic advantages to behavioral symptoms of autism spectrum disorder and fetal alcohol spectrum disorder, and to the severe nausea and vomiting in hyperemesis gravidarum. The use of medical cannabis in children and pregnant women should be further discussed and researched in this patient population.

摘要

近年来,由于诉讼和伦理方面的担忧,大麻在医疗用途上的增加很大程度上忽视了儿童和孕妇。然而,在过去几年中,医学上观察到越来越多的儿童因自闭症谱系障碍(ASD)和胎儿酒精谱系障碍(FASD)而接受大麻治疗,以及孕妇因妊娠剧吐(HG)而接受大麻治疗。本综述介绍了通过这项研究发现的主要结果。具体而言,大麻可能对自闭症谱系障碍和胎儿酒精谱系障碍的行为症状以及妊娠剧吐中的严重恶心和呕吐具有治疗优势。在这一患者群体中,应进一步讨论和研究儿童和孕妇使用医用大麻的情况。