污染、颗粒物质与痴呆症：一个假设的致病途径。
Pollution, Particles, and Dementia: A Hypothetical Causative Pathway.
机构信息
Department of Environmental Medicine, Aberdeen University, Aberdeen AB25 2ZP, UK.
Institute of Occupational Medicine, Edinburgh EH14 4AP, UK.
出版信息
Int J Environ Res Public Health. 2020 Jan 30;17(3):862. doi: 10.3390/ijerph17030862.
Abstract
Epidemiological studies of air pollution have shown associations between exposure to particles and dementia. The mechanism of this is unclear. As these seem unlikely in terms of the very small dose likely to reach the brain in usual Western urban circumstances, we extend our 1995 hypothetical explanation of the association of air pollution with cardiac deaths as a plausible alternative explanation of its associations with dementia.
摘要
流行病学研究表明，暴露于空气中的颗粒物与痴呆之间存在关联。但其中的机制尚不清楚。由于在西方城市的一般环境中，到达大脑的剂量非常小，因此这些关联似乎不太可能，因此我们扩展了我们在 1995 年提出的空气污染与心脏病死亡之间关联的假设性解释，作为其与痴呆症关联的另一种合理解释。
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