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沙尘带(加那利群岛)的撒哈拉沙尘事件及其与心力衰竭患者院内死亡率的观察性关联

Saharan Dust Events in the Dust Belt -Canary Islands- and the Observed Association with in-Hospital Mortality of Patients with Heart Failure.

作者信息

Dominguez-Rodriguez Alberto, Baez-Ferrer Néstor, Rodríguez Sergio, Avanzas Pablo, Abreu-Gonzalez Pedro, Terradellas Enric, Cuevas Emilio, Basart Sara, Werner Ernest

机构信息

Department of Cardiology, Hospital Universitario de Canarias, 38320 La Cuesta, Santa Cruz de Tenerife, Spain.

Faculty of Health Sciences, Universidad Europea de Canarias, Calle Inocencio García 1, 38300 La Orotava, Santa Cruz de Tenerife, Spain.

出版信息

J Clin Med. 2020 Jan 30;9(2):376. doi: 10.3390/jcm9020376.

Abstract

Recent studies have found increases in the cardiovascular mortality rates during poor air quality events due to outbreaks of desert dust. In Tenerife, we collected (2014-2017) data in 829 patients admitted with a heart failure diagnosis in the Emergency Department of the University Hospital of the Canaries. In this region, concentrations of PM and PM are usually low (~20 and 10 µg/m), but they increase to 360 and 115 μg/m, respectively, during Saharan dust events. By using statistical tools (including multivariable logistic regressions), we compared in-hospital mortality of patients with heart failure and exposure to PM and PM during dust and no-dust events. We found that 86% of in-hospital heart failure mortality cases occurred during Saharan dust episodes that resulted in PM > 50 µg/m (interquartile range: 71-96 µg/m). A multivariate analysis showed that, after adjusting for other covariates, exposure to Saharan dust events associated with PM > 50 µg/m was an independent predictor of heart failure in-hospital mortality (OR = 2.79, 95% CI (1.066-7.332), = 0.03). In conclusion, this study demonstrates that exposure to high Saharan dust concentrations is independently associated with in-hospital mortality in patients with heart failure.

摘要

最近的研究发现,由于沙漠尘埃爆发,空气质量差的事件期间心血管死亡率有所上升。在特内里费岛,我们收集了(2014 - 2017年)加那利群岛大学医院急诊科收治的829例心力衰竭诊断患者的数据。在该地区,PM和PM的浓度通常较低(约20和10μg/m),但在撒哈拉尘埃事件期间,它们分别增至360和115μg/m。通过使用统计工具(包括多变量逻辑回归),我们比较了心力衰竭患者在尘埃事件和无尘埃事件期间的住院死亡率以及暴露于PM和PM的情况。我们发现,86%的心力衰竭住院死亡病例发生在撒哈拉尘埃事件期间,此时PM>50μg/m(四分位间距:71 - 96μg/m)。多变量分析表明,在调整其他协变量后,暴露于与PM>50μg/m相关的撒哈拉尘埃事件是心力衰竭住院死亡率的独立预测因素(OR = 2.79,95%CI(1.066 - 7.332),P = 0.03)。总之,本研究表明,暴露于高浓度的撒哈拉尘埃与心力衰竭患者的住院死亡率独立相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/105a/7073718/c9e975cfdeb3/jcm-09-00376-g001.jpg

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