Department of Cybernetics, Nanotechnology and Data Processing, Silesian University of Technology, PL44100 Gliwice, Poland.
Łukasiewicz Research Network - Institute of Medical Technology and Equipment, PL 41800 Zabrze, Poland.
Sensors (Basel). 2020 Jan 30;20(3):765. doi: 10.3390/s20030765.
Atrial fibrillation (AF) is a serious heart arrhythmia leading to a significant increase of the risk for occurrence of ischemic stroke. Clinically, the AF episode is recognized in an electrocardiogram. However, detection of asymptomatic AF, which requires a long-term monitoring, is more efficient when based on irregularity of beat-to-beat intervals estimated by the heart rate (HR) features. Automated classification of heartbeats into AF and non-AF by means of the Lagrangian Support Vector Machine has been proposed. The classifier input vector consisted of sixteen features, including four coefficients very sensitive to beat-to-beat heart changes, taken from the fetal heart rate analysis in perinatal medicine. Effectiveness of the proposed classifier has been verified on the MIT-BIH Atrial Fibrillation Database. Designing of the LSVM classifier using very large number of feature vectors requires extreme computational efforts. Therefore, an original approach has been proposed to determine a training set of the smallest possible size that still would guarantee a high quality of AF detection. It enables to obtain satisfactory results using only 1.39% of all heartbeats as the training data. Post-processing stage based on aggregation of classified heartbeats into AF episodes has been applied to provide more reliable information on patient risk. Results obtained during the testing phase showed the sensitivity of 98.94%, positive predictive value of 98.39%, and classification accuracy of 98.86%.
心房颤动(AF)是一种严重的心律失常,会显著增加发生缺血性中风的风险。临床上,在心电图中可以识别 AF 发作。然而,基于通过心率(HR)特征估计的心跳间不规则性来检测需要长期监测的无症状 AF 更有效。已经提出了通过拉格朗日支持向量机自动将心跳分类为 AF 和非 AF 的方法。分类器输入向量由十六个特征组成,包括四个非常敏感的心率变化的系数,取自围产期医学中的胎儿心率分析。所提出的分类器的有效性已在麻省理工学院-贝斯以色列医院心房颤动数据库上得到验证。使用大量特征向量设计 LSVM 分类器需要极端的计算能力。因此,提出了一种原始方法来确定最小的训练集大小,仍然可以保证 AF 检测的高质量。它可以使用仅 1.39%的所有心跳作为训练数据来获得令人满意的结果。基于将分类的心跳聚合成 AF 发作的后处理阶段已被应用于提供更可靠的患者风险信息。在测试阶段获得的结果显示敏感性为 98.94%,阳性预测值为 98.39%,分类准确率为 98.86%。