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用于从心电图检测心房颤动的机器学习:系统评价与荟萃分析

Machine Learning for Detecting Atrial Fibrillation from ECGs: Systematic Review and Meta-Analysis.

作者信息

Xie Chenggong, Wang Zhao, Yang Chenglong, Liu Jianhe, Liang Hao

机构信息

Hunan Provincial Key Laboratory of TCM Diagnostics, Hunan University of Chinese Medicine, 410208 Changsha, Hunan, China.

School of Acupuncture and Tui-na and Rehabilitation, Hunan University of Chinese Medicine, 410208 Changsha, Hunan, China.

出版信息

Rev Cardiovasc Med. 2024 Jan 8;25(1):8. doi: 10.31083/j.rcm2501008. eCollection 2024 Jan.

DOI:10.31083/j.rcm2501008
PMID:39077651
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11262392/
Abstract

BACKGROUND

Atrial fibrillation (AF) is a common arrhythmia that can result in adverse cardiovascular outcomes but is often difficult to detect. The use of machine learning (ML) algorithms for detecting AF has become increasingly prevalent in recent years. This study aims to systematically evaluate and summarize the overall diagnostic accuracy of the ML algorithms in detecting AF in electrocardiogram (ECG) signals.

METHODS

The searched databases included PubMed, Web of Science, Embase, and Google Scholar. The selected studies were subjected to a meta-analysis of diagnostic accuracy to synthesize the sensitivity and specificity.

RESULTS

A total of 14 studies were included, and the forest plot of the meta-analysis showed that the pooled sensitivity and specificity were 97% (95% confidence interval [CI]: 0.94-0.99) and 97% (95% CI: 0.95-0.99), respectively. Compared to traditional machine learning (TML) algorithms (sensitivity: 91.5%), deep learning (DL) algorithms (sensitivity: 98.1%) showed superior performance. Using multiple datasets and public datasets alone or in combination demonstrated slightly better performance than using a single dataset and proprietary datasets.

CONCLUSIONS

ML algorithms are effective for detecting AF from ECGs. DL algorithms, particularly those based on convolutional neural networks (CNN), demonstrate superior performance in AF detection compared to TML algorithms. The integration of ML algorithms can help wearable devices diagnose AF earlier.

摘要

背景

心房颤动(AF)是一种常见的心律失常,可导致不良心血管结局,但往往难以检测。近年来,使用机器学习(ML)算法检测AF变得越来越普遍。本研究旨在系统评价和总结ML算法在心电图(ECG)信号中检测AF的总体诊断准确性。

方法

检索的数据库包括PubMed、Web of Science、Embase和谷歌学术。对所选研究进行诊断准确性的荟萃分析,以综合敏感性和特异性。

结果

共纳入14项研究,荟萃分析的森林图显示,合并敏感性和特异性分别为97%(95%置信区间[CI]:0.94-0.99)和97%(95%CI:0.95-0.99)。与传统机器学习(TML)算法(敏感性:91.5%)相比,深度学习(DL)算法(敏感性:98.1%)表现更优。单独或联合使用多个数据集和公共数据集的性能略优于使用单个数据集和专有数据集。

结论

ML算法对从ECG中检测AF有效。与TML算法相比,DL算法,尤其是基于卷积神经网络(CNN)的算法,在AF检测中表现更优。ML算法的整合有助于可穿戴设备更早地诊断AF。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca39/11262392/9da8a37a2505/2153-8174-25-1-008-g6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca39/11262392/609f4342f63e/2153-8174-25-1-008-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca39/11262392/3eee995aae95/2153-8174-25-1-008-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca39/11262392/4948a489b006/2153-8174-25-1-008-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca39/11262392/45b0e5f44e22/2153-8174-25-1-008-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca39/11262392/8e8dd5d6233b/2153-8174-25-1-008-g5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca39/11262392/9da8a37a2505/2153-8174-25-1-008-g6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca39/11262392/609f4342f63e/2153-8174-25-1-008-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca39/11262392/3eee995aae95/2153-8174-25-1-008-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca39/11262392/4948a489b006/2153-8174-25-1-008-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca39/11262392/45b0e5f44e22/2153-8174-25-1-008-g4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca39/11262392/8e8dd5d6233b/2153-8174-25-1-008-g5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca39/11262392/9da8a37a2505/2153-8174-25-1-008-g6.jpg

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本文引用的文献

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Sensors (Basel). 2022 Nov 8;22(22):8588. doi: 10.3390/s22228588.
2
Identification of Patients with Potential Atrial Fibrillation during Sinus Rhythm Using Isolated P Wave Characteristics from 12-Lead ECGs.利用12导联心电图的孤立P波特征识别窦性心律时潜在房颤患者
J Pers Med. 2022 Sep 29;12(10):1608. doi: 10.3390/jpm12101608.
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Detection of Atrial Fibrillation in a Large Population Using Wearable Devices: The Fitbit Heart Study.
利用可穿戴设备在大人群中检测心房颤动:Fitbit 心脏研究。
Circulation. 2022 Nov 8;146(19):1415-1424. doi: 10.1161/CIRCULATIONAHA.122.060291. Epub 2022 Sep 23.
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Deepaware: A hybrid deep learning and context-aware heuristics-based model for atrial fibrillation detection.深智:一种基于深度学习和上下文感知启发式的混合模型,用于心房颤动检测。
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Short Single-Lead ECG Signal Delineation-Based Deep Learning: Implementation in Automatic Atrial Fibrillation Identification.基于短单导联心电图信号分割的深度学习:在自动心房颤动识别中的应用。
Sensors (Basel). 2022 Mar 17;22(6):2329. doi: 10.3390/s22062329.
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Compressed Deep Learning to Classify Arrhythmia in an Embedded Wearable Device.基于压缩的深度学习在嵌入式可穿戴设备中的心律失常分类。
Sensors (Basel). 2022 Feb 24;22(5):1776. doi: 10.3390/s22051776.
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Smartphone and new tools for atrial fibrillation diagnosis: evidence for clinical applicability.智能手机和心房颤动诊断新工具:临床适用性证据。
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