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沙特阿拉伯国家警卫初级保健中心就诊孕妇中妊娠期糖尿病的患病率及危险因素。

Prevalence and risk factors of gestational diabetes mellitus among pregnant patients visiting National Guard primary health care centers in Saudi Arabia.

机构信息

College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Kingdom of Saudi Arabia. E-mail.

出版信息

Saudi Med J. 2020 Feb;41(2):144-150. doi: 10.15537/smj.2020.2.24842.

DOI:10.15537/smj.2020.2.24842
PMID:32020147
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7841639/
Abstract

To measure the prevalence of gestational diabetes mellitus (GDM) and its risk factors in Saudi Arabia, in comparison with developed and developing countries worldwide.  Methods: We enrolled pregnant women aged 15-45 years who visited 3 National Guard-Health Affairs' primary health care centers in Jeddah, Saudi Arabia between January 2017 and December 2017. We used stratified samples and computer-generated random numbers to collect data. This data includes demographics, obstetric history, blood pressure, non-fasting 1-hour glucose challenge test (GCT), 3-hour oral glucose tolerance test (OGTT), hemoglobin level, rubella immunization status, hepatitis B surface antigen status, urinalysis results, and labor, and delivery notes. We categorized the patients into 2 groups, GDM and non-GDM, based on GCT and OGTT. Results: We enrolled 347 women in the study (mean age, 28.8±6 years; range, 18-45 years). On GCT, 36.6% of women showed abnormal values and 6.9% exhibited diagnostic values. Oral glucose tolerance test indicated impairment in 18.7% of patients and a diagnostic finding in 15% of patients. Women diagnosed with GDM tended to be older and have greater body mass index (BMI) values. Conclusion: The prevalence of GDM in Saudi Arabia is high compared to other countries. Advanced maternal age and higher BMI values were associated with increased prevalence of GDM. Thus, early prevention and management of GDM is vital to minimize the risks to both the mother and fetus.

摘要

为了衡量沙特阿拉伯妊娠糖尿病(GDM)的流行率及其危险因素,并与全球发达国家和发展中国家进行比较。方法:我们招募了 2017 年 1 月至 12 月期间在沙特阿拉伯吉达的 3 个国民警卫队-卫生事务初级保健中心就诊的 15-45 岁的孕妇。我们使用分层样本和计算机生成的随机数收集数据。这些数据包括人口统计学、产科史、血压、非空腹 1 小时葡萄糖挑战试验(GCT)、3 小时口服葡萄糖耐量试验(OGTT)、血红蛋白水平、风疹免疫状况、乙型肝炎表面抗原状况、尿液分析结果以及分娩和分娩记录。我们根据 GCT 和 OGTT 将患者分为 GDM 和非 GDM 两组。结果:我们共招募了 347 名研究对象(平均年龄 28.8±6 岁;范围 18-45 岁)。在 GCT 中,36.6%的女性表现出异常值,6.9%表现出诊断值。口服葡萄糖耐量试验表明 18.7%的患者受损,15%的患者出现诊断发现。被诊断为 GDM 的女性往往年龄较大,体重指数(BMI)值较高。结论:与其他国家相比,沙特阿拉伯的 GDM 患病率较高。产妇年龄较大和 BMI 值较高与 GDM 患病率增加有关。因此,早期预防和管理 GDM 对于最大限度地降低母婴风险至关重要。

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