Southern Illinois University School of Medicine, Springfield, USA.
The University of Iowa Carver College of Medicine, Lowa, USA.
Hand (N Y). 2020 Sep;15(5):599-607. doi: 10.1177/1558944719898801. Epub 2020 Feb 5.
Carpal tunnel syndrome and ulnar neuropathy are such common maladies affecting the upper extremties that they often become the default diagnosis when patients complain of numbness, pain, or weakness of the hands. While often correct, there are a number of other conditions that can also cause sensory or motor loss of the hands, which should be considered when appropriate, as they can mimic upper extremity entrapment syndromes. In this review, we will discuss such mimics, including Charcot-Marie-Tooth disease, multifocal motor neuropathy, hereditary neuropathy with pressure palsies, mononeuropathy multiplex, Lewis-Sumner syndrome, brachial plexitis (Parsonage-Turner syndrome), myotonic dystrophy, inclusion body myopathy, and distal myopathy of Welander. We will discuss the clinical presentation, as well as diagnostic testing, treatment (if available), and prognosis. The objective is to provide a differential diagnosis for those patients who do not fit well clinically or respond to usual therapy for entrapment neuropathy of the upper extremities.
腕管综合征和尺神经病变是常见的上肢疾病，当患者出现手部麻木、疼痛或无力时，它们通常是默认的诊断。虽然通常是正确的，但还有许多其他疾病也会导致手部感觉或运动丧失，在适当的情况下应考虑这些疾病，因为它们可能模仿上肢压迫综合征。在这篇综述中，我们将讨论这些类似的疾病，包括遗传性运动感觉神经病、多发性运动神经病、遗传性压迫易发性神经病、多发性单神经病、Lewis-Sumner 综合征、臂丛神经炎（Parsonage-Turner 综合征）、肌强直性营养不良、包涵体肌病和 Welander 远端肌病。我们将讨论临床表现以及诊断性检查、治疗（如有）和预后。目的是为那些不符合上肢压迫性神经病的临床特征或对常规治疗反应不佳的患者提供鉴别诊断。
