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单节段椎体切除与双节段椎间盘切除治疗脊髓型颈椎病的生物力学比较:有限元分析。

Biomechanical Comparison of 1-Level Corpectomy and 2-Level Discectomy for Cervical Spondylotic Myelopathy: A Finite Element Analysis.

机构信息

Department of Orthopedic Surgery, The 2nd Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China (mainland).

State Key Laboratory for Manufacturing Systems Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an, Shaanxi, China (mainland).

出版信息

Med Sci Monit. 2020 Feb 5;26:e919270. doi: 10.12659/MSM.919270.

DOI:10.12659/MSM.919270
PMID:32020914
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7020763/
Abstract

BACKGROUND Anterior cervical discectomy and fusion (ACDF) and anterior cervical corpectomy and fusion (ACCF) are effective treatments for cervical spondylotic myelopathy (CSM), but it is unclear which is better. In this study, we compared the biomechanical properties of 2-level ACDF and 1-level ACCF. MATERIAL AND METHODS An intact C3-C7 cervical spine model was developed and validated, then ACDF and ACCF simulation models were developed. We imposed 1.0 Nm moments and displacement-controlled loading on the C3 superior endplate. The range of motions (ROMs) of surgical and adjacent segments and von Mises stresses on endplates, fixation systems, bone-screw interfaces, and bone grafts were recorded. RESULTS ACDF and ACCF significantly reduced the surgical segmental ROMs to the same extent. ACCF induced much lower stress peaks in the fixation system and bone-screw interfaces and higher stress peaks on the bone graft. ACDF induced much lower stress peaks on the C4 inferior endplate and equivalent stress on the C6 superior endplate. There was no difference in the ROMs of surgical and adjacent segments and the intradiscal stress of adjacent levels between ACDF and ACCF. CONCLUSIONS Both ACDF and ACCF can provide satisfactory spinal stability. ACDF may be beneficial for subsidence resistance due to the lower stress peaks on the endplate. The ACCF may perform better in long-term stability and bone fusion owing to the lower stress peaks in the fixation system and bone-screw interfaces, and higher stress peaks in the bone graft.

摘要

背景

颈椎前路椎间盘切除融合术(ACDF)和颈椎前路椎体次全切除融合术(ACCF)是治疗脊髓型颈椎病(CSM)的有效方法,但哪种方法更优尚不清楚。本研究比较了 2 节段 ACDF 和 1 节段 ACCF 的生物力学特性。

材料与方法

建立并验证了完整的 C3-C7 颈椎模型,然后建立了 ACDF 和 ACCF 模拟模型。我们在 C3 上终板施加 1.0 Nm 的力矩和位移控制加载。记录手术节段和相邻节段的活动范围(ROM)以及终板、固定系统、骨-螺钉界面和骨移植物上的 von Mises 应力。

结果

ACDF 和 ACCF 显著降低了手术节段的 ROM,降低程度相同。ACCF 引起固定系统和骨-螺钉界面的峰值应力较低,而骨移植物的峰值应力较高。ACDF 引起 C4 下终板的峰值应力较低,C6 上终板的等效应力较高。ACDF 和 ACCF 在手术节段和相邻节段的 ROM 以及相邻节段椎间盘内的应力方面没有差异。

结论

ACDF 和 ACCF 均可提供满意的脊柱稳定性。由于终板上的峰值应力较低,ACDF 可能有利于沉降抵抗。由于固定系统和骨-螺钉界面的峰值应力较低,骨移植物的峰值应力较高,ACCF 可能在长期稳定性和骨融合方面表现更好。

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The most influential publications in cervical myelopathy.
颈椎病领域最具影响力的出版物。
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