Torres A, Puig de la Bellacasa J, Rodriguez-Roisin R, Jimenez de Anta M T, Agusti-Vidal A
Serveis de Pneumologia and Microbiologia, Hospital Clinic, Facultat de Medicina, Universitat de Barcelona, Spain.
Am Rev Respir Dis. 1988 Jul;138(1):117-20. doi: 10.1164/ajrccm/138.1.117.
A new guiding technique, Metras catheter (MC), for blindly introducing a telescoping plugged catheter (TPC) was applied to 25 mechanically ventilated patients with suspected bacterial pneumonia (BPN). Results obtained with TPC-MC were compared with those obtained with TPC using a conventional fiberoptic bronchoscope (FB) in random order. The diagnosis of BPN was definitely confirmed in 18 patients. In 7 patients, all TPC samples (MC and FB) were sterile, and a diagnosis other than BPN was proved. In the former group, colony-forming units equal to or greater than 10(3)/ml of one or more microorganisms were obtained in 61% of TPC-MC and in 66% of TPC-FB samples. These percentages increased to 64 and 71%, respectively, when 4 patients with previous antibiotic treatment were excluded from the study group. Agreement was observed between microorganisms cultured from both TPC samples in 11 of 18 patients with proved BPN (61%). Complete disparity was seen only in 2 patients (11%). Two patients developed a self-limiting hemoptysis after the TPC procedure (MC and FB, respectively). We conclude that TPC-MC is both a sensitive and specific technique for the diagnosis of BPN in mechanically ventilated patients. Because the diagnostic value of TPC-MC is similar to that of TPC-FB, we propose that the MC be used in patients receiving mechanical ventilation when the FB is not available. The simplicity and lower cost of this new system are important advantages to be considered over the fiberoptic bronchoscope.
一种用于盲目插入可伸缩堵塞导管(TPC)的新型引导技术——梅特拉斯导管(MC),被应用于25例疑似细菌性肺炎(BPN)的机械通气患者。将TPC-MC获得的结果与使用传统纤维支气管镜(FB)的TPC获得的结果按随机顺序进行比较。18例患者被明确诊断为BPN。7例患者的所有TPC样本(MC和FB)均无菌,证实诊断为非BPN。在前一组中,61%的TPC-MC样本和66%的TPC-FB样本中获得了一种或多种微生物的菌落形成单位等于或大于10³/ml。当4例先前接受过抗生素治疗的患者被排除在研究组之外时,这些百分比分别增至64%和71%。在18例确诊为BPN的患者中,11例(61%)的两个TPC样本培养出的微生物一致。仅2例患者(11%)出现完全不同的结果。2例患者在TPC操作后(分别为MC和FB)出现了自限性咯血。我们得出结论,TPC-MC是诊断机械通气患者BPN的一种敏感且特异的技术。由于TPC-MC的诊断价值与TPC-FB相似,我们建议在无法使用FB时,将MC用于接受机械通气的患者。与纤维支气管镜相比,这种新系统的简单性和低成本是需要考虑的重要优势。