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在瑞典,前交叉韧带重建术中并没有普遍使用血栓预防和长期抗生素预防:一项全国范围内的 ACL 外科医生调查。

There is no general use of thromboprophylaxis and prolonged antibiotic prophylaxis in anterior cruciate ligament reconstruction: a nation-wide survey of ACL surgeons in Sweden.

机构信息

Karolinska Institutet, Stockholm, Sweden.

Stockholm Sports Trauma Research Center, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2020 Aug;28(8):2535-2542. doi: 10.1007/s00167-020-05851-7. Epub 2020 Feb 5.

Abstract

PURPOSE

The use of prophylaxis for thromboembolism and infection in anterior cruciate ligament (ACL) reconstruction is not well documented and no general guidelines have been established. The aim of this study was to evaluate the ACL surgeons' individual strategies of thromboprophylaxis, use of prolonged antibiotic prophylaxis and vancomycin-soaked ACL grafts, and if its use is supported in the current literature. Additionally, the rationale for use of tourniquet was analysed.

METHODS

Questionnaires were distributed to all Swedish ACL surgeons who are registered in the Swedish Knee Ligament Register (SKLR), asking about prescription of thromboprophylaxis, prolonged antibiotic prophylaxis, the use of vancomycin-soaked graft and the use of a tourniquet during surgery. The responses were assessed for agreement and the thromboprophylaxis data were analysed in relation to the 2016 SKLR data.

RESULTS

115 (75%) ACL surgeons responded to the survey. 81.7% prescribed thromboprophylaxis only when risk factors, such as history of thrombosis and the use of oral contraceptives, were present. Female gender, older age and admitted patient were considered the risk factors with the lowest impact. The respondents were generally restrictive regarding the use of prolonged antibiotic prophylaxis. The use of vancomycin-soaked graft was used by only nine (8%) surgeons representing 406 (13%) of the surgeries.

CONCLUSION

Swedish ACL surgeons are generally restrictive using thromboprophylaxis and only when risk factors are present. However, there is a lack of consensus in how to weigh the different risk factors and it does not completely adhere to the existing literature. Prolonged antibiotic prophylaxis is rarely used and the use of vancomycin soaking of graft is very limited and applies only to a small number of surgeons. The use of tourniquet is common. There is a need for ACL-specific guidelines regarding the use of thromboprophylaxis.

LEVEL OF EVIDENCE

IV.

摘要

目的

前交叉韧带(ACL)重建中预防血栓栓塞和感染的使用方法没有得到很好的记录,也没有建立一般的指南。本研究的目的是评估 ACL 外科医生在预防血栓形成、延长抗生素预防、万古霉素浸泡 ACL 移植物以及其在当前文献中的使用情况方面的个人策略。此外,还分析了使用止血带的基本原理。

方法

向所有在瑞典 ACL 登记册(SKLR)注册的瑞典 ACL 外科医生分发问卷,询问他们关于预防血栓形成、延长抗生素预防、使用万古霉素浸泡移植物和在手术中使用止血带的处方。对回答进行了一致性评估,并根据 2016 年 SKLR 数据分析了预防血栓形成的数据。

结果

115 名(75%)ACL 外科医生对调查做出了回应。81.7%的医生仅在存在血栓形成史和使用口服避孕药等危险因素时才开具预防血栓形成的处方。女性、年龄较大和住院患者被认为是风险因素,但影响最小。受访者通常对延长抗生素预防的使用持限制态度。只有 9 名(8%)外科医生使用万古霉素浸泡移植物,代表 406 例(13%)手术。

结论

瑞典 ACL 外科医生通常在存在危险因素时才会限制使用预防血栓形成的方法。但是,如何权衡不同的风险因素缺乏共识,并且不完全符合现有的文献。延长抗生素预防的使用很少,万古霉素浸泡移植物的使用非常有限,仅适用于少数外科医生。止血带的使用很常见。需要制定 ACL 特异性指南来指导预防血栓形成的使用。

证据等级

IV。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fada/7429518/78aca7e427e4/167_2020_5851_Fig1_HTML.jpg

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