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外科医生在 ACL 研究组中对前浸泡万古霉素 ACL 肌腱移植物的实践模式进行调查。

Surgeon practice patterns for pre-soaking ACL tendon grafts in vancomycin: a survey of the ACL study group.

机构信息

Department of Orthopaedic Surgery, Stanford University School of Medicine, 341 Galvez St, Mail Code 6175, Stanford, CA, 94305, USA.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2021 Jun;29(6):1920-1926. doi: 10.1007/s00167-020-06265-1. Epub 2020 Sep 9.

Abstract

PURPOSE

To survey members of The ACL study group to determine the current practice patterns surrounding the technique of pre-soaking ACL grafts in vancomycin.

METHODS

A web-based questionnaire was distributed to members of the ACL Study Group. Questions included the use of vancomycin solution for graft soaking during ACL reconstruction, their protocol for soaking the graft, vancomycin concentration utilized, graft choices, and concerns with the technique.

RESULTS

Sixty-six (57%) ACL surgeons completed the survey. Approximately one-third (37.9%) of respondents currently pre-soak their ACL grafts in vancomycin prior to implantation, with 60% of these surgeons being from Europe. Seventy-six percent have adopted this practice within the past 5 years. The majority of surgeons wrap the graft in a vancomycin-soaked gauze prior to implantation (56%), soak for a variable amount of time before implantation (56%), use a concentration of 5 mg/mL (68%), and soak hamstring grafts (92%). Concerns included the mechanical properties of the graft (35%), cost of vancomycin (23%), availability (12%), and antibiotic resistance (9%).

CONCLUSION

This survey demonstrates that 37.9% of ACL study group members currently utilize vancomycin to pre-soak ACL tendon grafts as a means to decrease post-operative infection risk, with the majority of surgeons having implemented this practice within the past 5 years. The biggest concern towards using vancomycin was the mechanical properties of the graft after soaking.

LEVEL OF EVIDENCE

IV.

摘要

目的

调查 ACL 研究小组成员,以确定目前围绕 ACL 移植物预浸泡万古霉素技术的实践模式。

方法

通过网络向 ACL 研究小组成员分发问卷。问题包括在 ACL 重建期间使用万古霉素溶液浸泡移植物、他们的浸泡移植物方案、使用的万古霉素浓度、移植物选择以及对该技术的担忧。

结果

66 名(57%)ACL 外科医生完成了调查。约三分之一(37.9%)的受访者目前在植入前将 ACL 移植物预浸泡在万古霉素中,其中 60%的外科医生来自欧洲。76%的人在过去 5 年内采用了这种做法。大多数外科医生在植入前将移植物包裹在浸泡有万古霉素的纱布中(56%),在植入前浸泡一定时间(56%),使用 5mg/mL 的浓度(68%),并浸泡腘绳肌腱移植物(92%)。关注的问题包括移植物的机械性能(35%)、万古霉素的成本(23%)、供应情况(12%)和抗生素耐药性(9%)。

结论

这项调查表明,37.9%的 ACL 研究小组成员目前使用万古霉素预浸泡 ACL 肌腱移植物,以降低术后感染风险,大多数外科医生在过去 5 年内实施了这一做法。使用万古霉素的最大担忧是浸泡后移植物的机械性能。

证据水平

IV。

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