Department of Dentistry, London Health Sciences Centre, London, ON, Canada.
Department of Dentistry, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Head Neck Pathol. 2020 Dec;14(4):1139-1148. doi: 10.1007/s12105-020-01134-2. Epub 2020 Feb 5.
Primary intraoral angiosarcoma is an exceptionally rare malignancy of vascular origin which can be challenging to diagnose due to microscopic and immunohistochemical variability. A histopathologically challenging case of primary intraoral angiosarcoma, occurring in a pediatric patient is presented. A comprehensive review of the literature reveals that primary intraoral angiosarcomas occur with nearly equal frequency in males and females, affect the gingiva and the tongue most commonly and are treated primarily with surgery. As with angiosarcoma in other sites, primary intraoral angiosarcoma behaves aggressively with the majority of patients succumbing to their disease.
原发性口腔内血管肉瘤是一种极为罕见的血管源性恶性肿瘤，由于其在显微镜下和免疫组织化学方面存在可变性，因此诊断具有一定挑战性。本文呈现了一例发生于儿科患者的原发性口腔内血管肉瘤的病理挑战性病例。对文献的全面回顾表明，原发性口腔内血管肉瘤在男性和女性中的发病率几乎相等，最常累及牙龈和舌，主要通过手术治疗。与其他部位的血管肉瘤一样，原发性口腔内血管肉瘤具有侵袭性，大多数患者最终死于该病。
