Department of Dermatology, Venereology and Allergology, Leipzig Interdisciplinary Center for Allergology - LICA-CAC, University of Leipzig, Germany.
J Dtsch Dermatol Ges. 2020 Feb;18(2):93-102. doi: 10.1111/ddg.14029.
Atopic dermatitis (AD) is a chronic inflammatory disease that may be associated with a number of comorbidities including psychosocial disorders, which are the primary focus of this article. The data presented is based on a literature search in PubMed and subsequent screening of relevant review articles and guidelines. There is a greater prevalence of depression, anxiety, sleep disorders and suicidal ideation among individuals with AD. The disease negatively impacts patients' quality of life. Children with AD have been shown to more commonly exhibit signs of attention-deficit/hyperactivity disorder. Only little data exists on the association of AD with schizophrenia, eating disorders or obsessive-compulsive disorder. There is a great need for research in the field of AD-related comorbidities, especially with respect to the question as to whether and how novel treatment options may potentially affect these comorbidities.
特应性皮炎（AD）是一种慢性炎症性疾病，可能与许多合并症相关，包括本文的主要重点——精神社会障碍。本文的数据基于在 PubMed 中进行的文献检索，以及对相关综述文章和指南的后续筛选。患有 AD 的个体中，抑郁、焦虑、睡眠障碍和自杀意念的发生率更高。该疾病会降低患者的生活质量。研究表明，患有 AD 的儿童更常出现注意力缺陷/多动障碍的迹象。AD 与精神分裂症、饮食失调或强迫症之间的关联仅有少量数据。AD 相关合并症领域的研究需求巨大，特别是关于新型治疗选择是否以及如何可能影响这些合并症的问题。
