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抑郁症与皮肤自身免疫性疾病。

Depressive Disorder and Dermatological Autoimmune Diseases.

作者信息

Peła Zuzanna, Gałecka Maria, Murgrabia Agnieszka, Kondratowicz Aneta, Gałecki Piotr

机构信息

Department of Adult Psychiatry, Medical University of Lodz, 92-213 Lodz, Poland.

出版信息

J Clin Med. 2024 May 30;13(11):3224. doi: 10.3390/jcm13113224.

Abstract

Depressive disorders are a growing problem worldwide. They are also characterized by high comorbidity, including from the circle of dermatological diseases. Autoimmune diseases seem to be particularly correlated with depressive comorbidity, raising the question of their possible common pathomechanism. The PubMed database was searched, focusing on results published after 2016. A particular reciprocal correlation of depressive disorders with psoriasis, atopic dermatitis, alopecia areata, impetigo, lupus and systemic scleroderma was found. One possible explanation for the co-occurrence of the above diseases is that the inflammatory theory may be applicable to depression, the various elements of which also apply to autoimmune diseases.

摘要

抑郁症在全球范围内是一个日益严重的问题。它们还具有高共病性的特点,包括来自皮肤病领域。自身免疫性疾病似乎与抑郁共病特别相关,这就引发了它们可能存在共同病理机制的问题。我们检索了PubMed数据库,重点关注2016年以后发表的结果。发现抑郁症与银屑病、特应性皮炎、斑秃、脓疱病、狼疮和系统性硬化症之间存在特定的相互关联。上述疾病同时出现的一种可能解释是,炎症理论可能适用于抑郁症,其中的各种因素也适用于自身免疫性疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1edc/11172791/bc5d271bdc09/jcm-13-03224-g001.jpg

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