在中国的血清流行率及危险因素的识别。

Seroprevalence of and Identification of Risk Factors in China.

机构信息

State Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.

The Qinghuangdao Municipal Center for Disease Prevention and Control, Qinhuangdao 066000, Hebei, China.

出版信息

Biomed Environ Sci. 2020 Jan 20;33(1):72-75. doi: 10.3967/bes2020.011.

DOI:10.3967/bes2020.011

PMID:32029063

Abstract

Serum samples were tested for IgG antibodies using indirect immunofluorescence assays. We then analyzed associated risk factors. Serum samples were considered positive when reactive at a dilution of more than 1:320. Differences between groups and risk factors associated with exposure were statistically analyzed using Chi-square tests and the generalized linear model. 122 of 1,260 samples (9.68%) were positive for infection. The infection rate ranged from 0% to 30.43% and differed significantly among age groups ( < 0.01); infection rate in the 50-59 years group was significantly higher than that in other age groups. The seroprevalence of varied significantly among sites within the four provinces, and the infection rate of field workers was significantly higher than that of urban workers.

摘要

血清样本采用间接免疫荧光法检测 IgG 抗体。然后，我们分析了相关的危险因素。当血清样本在稀释度超过 1:320 时出现反应，则被认为是阳性。使用卡方检验和广义线性模型对组间差异和与暴露相关的危险因素进行统计学分析。在 1220 份样本中（9.68%）有 122 份呈感染阳性。感染率从 0%到 30.43%不等，且在不同年龄组之间有显著差异（<0.01）；50-59 岁组的感染率明显高于其他年龄组。四个省份内不同地点的血清阳性率差异显著，且野外工作者的感染率明显高于城市工作者。