对日本临床疑似猫抓病患者、心血管疾病患者以及健康兽医专业学生进行汉赛巴尔通体感染的血清学调查。

Serological investigation of Bartonella henselae infections in clinically cat-scratch disease-suspected patients, patients with cardiovascular diseases, and healthy veterinary students in Japan.

作者信息

Kikuchi Eisaku, Maruyama Soichi, Sakai Takeo, Tanaka Shigeo, Yamaguchi Fukumitsu, Hagiwara Toshikatsu, Katsube Yasuji, Mikami Takeshi

机构信息

Department of Veterinary Medicine, College Bioresource Sciences, Nihon University, Fujisawa, Kanagawa, Japan.

出版信息

Microbiol Immunol. 2002;46(5):313-6. doi: 10.1111/j.1348-0421.2002.tb02701.x.

DOI:10.1111/j.1348-0421.2002.tb02701.x

PMID:12139390

Abstract

Seroprevalence of Bartonella henselae was investigated in Japan in 48 individuals clinically suspected of having cat-scratch disease (CSD), 159 patients with cardiovascular diseases, and 129 healthy veterinary students. Of 48 CSD-suspected patients examined, 19 (39.6%) were positive for B. henselae-IgG and 4 (8.3%) for B. henselae-IgM. Of 159 patients with cardiovascular diseases, 5 (3.1%) were positive for B. henselae-IgG. In healthy veterinary students, 14 of 129 (10.9%) were positive for B. henselae-IgG and 1 (0.8%) for B. henselae-IgM. The positive rates of B. henselae-IgG and -IgM in CSD-suspected patients were significantly higher than in other sources. Most CSD-suspected and healthy individuals who were positive for B. henselae antibody had had some contacts with cats. In CSD-suspected patients, the B. henselae positive rate in females was significantly higher than in males, and high seropositive rates to B. henselae were found in younger age groups.

摘要

在日本，对48名临床疑似患有猫抓病（CSD）的个体、159名心血管疾病患者以及129名健康兽医专业学生进行了汉赛巴尔通体血清流行率调查。在接受检查的48名疑似CSD患者中，19人（39.6%）汉赛巴尔通体IgG呈阳性，4人（8.3%）汉赛巴尔通体IgM呈阳性。在159名心血管疾病患者中，5人（3.1%）汉赛巴尔通体IgG呈阳性。在健康兽医专业学生中，129人中有14人（10.9%）汉赛巴尔通体IgG呈阳性，1人（0.8%）汉赛巴尔通体IgM呈阳性。疑似CSD患者中汉赛巴尔通体IgG和IgM的阳性率显著高于其他来源。大多数汉赛巴尔通体抗体呈阳性的疑似CSD患者和健康个体都曾与猫有过接触。在疑似CSD患者中，女性的汉赛巴尔通体阳性率显著高于男性，且在较年轻年龄组中发现了较高的汉赛巴尔通体血清阳性率。