Zena and Michael A. Wiener Cardiovascular Institute/Marie-Josée and Henry R. Kravis Center for Cardiovascular Health, Icahn School of Medicine at Mount Sinai, New York, New York.
Peter Munk Cardiac Centre and the Heart and Stroke Richard Lewar Centre, University of Toronto, Toronto, Ontario, Canada.
J Am Coll Cardiol. 2020 Feb 11;75(5):539-555. doi: 10.1016/j.jacc.2019.11.046.
In the second part of this JACC State-of-the-Art Review, an early and sustainable preventive care plan is described for cardiometabolic-based chronic disease. This plan can improve cardiometabolic health by targeting early mechanistic events to decrease the risk for certain cardiovascular diseases (e.g., coronary heart disease, heart failure, and atrial fibrillation). Included are various prevention modalities, intensive lifestyle interventions, pharmacotherapy and cardiovascular outcome trial evidence, and bariatric/metabolic procedures. A tactical approach of implementing published clinical practice guidelines/algorithms for early behavioral, adiposity, and dysglycemia targeting is emphasized, as well as relevant educational and research implications.
在这篇 JACC 最新综述的第二部分，描述了一种基于心血管代谢的慢性疾病的早期和可持续的预防保健计划。该计划可以通过针对早期的机制事件来降低某些心血管疾病（如冠心病、心力衰竭和心房颤动）的风险，从而改善心血管代谢健康。其中包括各种预防方法、强化生活方式干预、药物治疗和心血管结局试验证据，以及减肥/代谢手术。强调了实施针对早期行为、肥胖和血糖异常的已发表临床实践指南/算法的策略方法，以及相关的教育和研究意义。
