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阻塞性睡眠呼吸暂停与心脏直视手术:对其发病率及对患者影响的综述

Obstructive sleep apnoea and open heart surgery: a review of its incidence and impact to patients.

作者信息

Krishnasamy Sivakumar, Sahid Saidah Mohd, Hashim Shahrul Amry, Singh Sukcharanjit, Chung Frances, Mokhtar Raja Amin Raja, Yin Wang Chew

机构信息

Cardiothoracic Unit, University of Malaya Medical Centre, Kuala Lumpur, Malaysia.

Department of General Surgery, Hospital Sultanah Bahiyah, Alor Setar, Kedah, Malaysia.

出版信息

J Thorac Dis. 2019 Dec;11(12):5453-5462. doi: 10.21037/jtd.2019.11.44.

Abstract

BACKGROUND

Obstructive sleep apnea (OSA) is a serious health disorder which contributes to cardiovascular complications, decreased work productivity, automobile accidents, and death. This condition is characterized by a temporary cessation of breathing resulting due to upper airway closure during a person's sleep. Strain to the heart caused by this repetitive hypoxic insult can lead to postoperative complications for patients undergoing heart surgery. Recognizing cardiac surgical patients with OSA is important. Early recognition and intervention such as use of BiPAP device can reduce the postoperative complications due to OSA.

METHODS

The aim of this study is to identify the incidence of unrecognized OSA in cardiac surgical patients. This is a retrospective analysis of a prospective data of the study which was done between July 2012 and July 2013 in University Malaya Medical Center. All patients undergoing elective cardiac surgery were recruited and the demographic data, questionnaire and the portable sleep study results were obtained. Patients were followed up till 30 days to record any complications. Data were entered in SPSS version 17 and analysis was done.

RESULTS

The incidence of OSA was 61.4% and 43.5% were moderate to severe OSA. There was male predominance of OSA (79%) with a mean age of 60 years. OSA subjects had shorter inter-incisor distance (4.18±0.6 cm) and larger waistline (94.1±12.1 cm). The STOP-Bang questionnaire has a sensitivity of 75.8% in predicting apnoa-hypopnea index (AHI) ≥5/hour.

CONCLUSIONS

OSA can be diagnosed with a simple screening questionnaire and a bedside portable sleep study. Cardiac patients diagnosed with OSA can be pre-emptively given extra attention in managing their postoperative care.

摘要

背景

阻塞性睡眠呼吸暂停(OSA)是一种严重的健康障碍,可导致心血管并发症、工作效率下降、交通事故和死亡。这种病症的特征是在人睡眠期间由于上呼吸道关闭而导致呼吸暂时停止。这种反复的低氧损伤对心脏造成的压力会导致心脏手术患者出现术后并发症。识别患有OSA的心脏手术患者很重要。早期识别和干预,如使用双水平气道正压通气(BiPAP)设备,可以减少因OSA导致的术后并发症。

方法

本研究的目的是确定心脏手术患者中未被识别的OSA的发生率。这是对2012年7月至2013年7月在马来亚大学医学中心进行的一项前瞻性研究数据的回顾性分析。招募了所有接受择期心脏手术的患者,并获取了人口统计学数据、问卷和便携式睡眠研究结果。对患者进行随访直至30天,记录任何并发症。数据录入SPSS 17版并进行分析。

结果

OSA的发生率为61.4%,其中43.5%为中度至重度OSA。OSA以男性为主(79%),平均年龄为60岁。OSA患者的门牙间距离较短(4.18±0.6厘米),腰围较大(94.1±12.1厘米)。STOP-Bang问卷在预测呼吸暂停低通气指数(AHI)≥5次/小时方面的敏感性为75.8%。

结论

OSA可以通过简单的筛查问卷和床边便携式睡眠研究进行诊断。被诊断患有OSA的心脏患者在术后护理管理中可以得到预先的额外关注。

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