Jekler J, Larkö O
Department of Dermatology, University of Göteborg, Sahlgren's Hospital, Sweden.
Br J Dermatol. 1988 Dec;119(6):697-705. doi: 10.1111/j.1365-2133.1988.tb03490.x.
UVB phototherapy of atopic dermatitis was investigated in two paired-comparison studies. In study I, 17 patients were treated for 8 weeks with ultraviolet B radiation (UVB) on one half of the body and with visible light (placebo) on the other. A severity score based on eight clinical variables was determined before, during and after treatment. The total score, pruritus score and overall evaluation score were significantly better on the UVB treated sides than on the placebo treated sides (P less than 0.001). In 13 patients the UVB treated side healed or improved considerably, while the placebo treated side improved considerably in one patient only. In study II, 25 patients were treated for 8 weeks with 0.8 of the minimal erythema dose (MED) of UVB on one half of the body and with 0.4 MED UVB on the other. No statistically significant differences between these dosage regimens were found.
在两项配对比较研究中对特应性皮炎的紫外线B光疗进行了调查。在研究I中，17名患者身体的一半接受紫外线B辐射（UVB）治疗8周，另一半接受可见光（安慰剂）治疗。在治疗前、治疗期间和治疗后根据八个临床变量确定严重程度评分。UVB治疗侧的总分、瘙痒评分和总体评估评分显著优于安慰剂治疗侧（P小于0.001）。13名患者中，UVB治疗侧愈合或有显著改善，而安慰剂治疗侧仅1名患者有显著改善。在研究II中，25名患者身体的一半接受0.8最小红斑量（MED）的UVB治疗8周，另一半接受0.4 MED的UVB治疗。未发现这些剂量方案之间有统计学上的显著差异。
