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Associations of Homer Scaffolding Protein 1 gene and psychological correlates with suicide attempts in Chinese: A pilot study of multifactorial risk model. Homer 支架蛋白 1 基因与心理相关因素与中国自杀未遂的关联:多因素风险模型的初步研究。
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建立组学护理科学与教育网络。

Establishing the Omics Nursing Science & Education Network.

机构信息

Program Officer, National Institutes of Health, National Institute of Nursing Research, Office of Extramural Programs, Bethesda, MD, USA.

XI, Research Geneticist, National Institutes of Health, National Cancer Institute, Center for Cancer Research, Genetics Branch, Bethesda, MD, USA.

出版信息

J Nurs Scholarsh. 2020 Mar;52(2):192-200. doi: 10.1111/jnu.12541. Epub 2020 Feb 6.

DOI:10.1111/jnu.12541
PMID:32030867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7398601/
Abstract

PURPOSE

To establish a website to advance nursing research and education involving omics technologies and methodologies through facilitating collaborations, use of existing data and samples, mentoring, and access to training opportunities.

METHODS

The Omics Nursing Science & Education Network (ONSEN) website was established following identification of gaps in omics nursing infrastructure and resources that could be addressed via a concerted, collaborative effort. ONSEN content was created using input from a workgroup of experts in genomics and other omics, education, practice, and nursing research. Alpha testing was conducted with workgroup members, followed by website refinements and enhancements, and subsequent beta testing by potential end users. ONSEN was launched in August 2018.

FINDINGS

ONSEN has three main sections. The Education and Training section provides information on mentoring and pre- or postdoctoral opportunities in addition to a knowledge matrix to advance education and skills in genomic nursing science. The Research Collaborations section promotes awareness of ongoing omics nursing research in order to foster collaborations and sharing of samples or data among investigators with programs in omics nursing research or an interest in developing such programs. The Common Data Elements (CDE) section provides information on the benefits of incorporating CDEs into nursing science as well as links to National Institutes of Health resources to facilitate use of CDEs.

CONCLUSIONS

ONSEN provides opportunities for nurse scientists and trainees to leverage samples and datasets, locate mentors and pre- or postdoctoral positions, further the use of CDEs, and enhance education and skills for integrating omics into nursing science.

CLINICAL RELEVANCE

Advancing omics nursing science via ONSEN resources will accelerate the elucidation of the molecular underpinnings of disease and associated symptoms as well as inform the development of rapidly translatable, personalized intervention strategies, grounded in biological mechanisms, for improved health outcomes across populations and the lifespan.

摘要

目的

通过促进合作、利用现有数据和样本、指导和获得培训机会,建立一个网站来推进涉及组学技术和方法的护理研究和教育。

方法

在确定了可以通过协调一致的合作努力解决的组学护理基础设施和资源方面的差距后,建立了组学护理科学与教育网络(ONSEN)网站。ONSEN 内容是使用基因组学和其他组学、教育、实践以及护理研究方面的专家工作组的输入创建的。对工作组的成员进行了 alpha 测试,然后对网站进行了改进和增强,随后由潜在的最终用户进行了 beta 测试。ONSEN 于 2018 年 8 月推出。

发现

ONSEN 有三个主要部分。教育和培训部分提供有关指导和博士后机会的信息,此外还有一个知识矩阵,旨在促进基因组护理科学的教育和技能。研究合作部分旨在提高对正在进行的组学护理研究的认识,以促进合作,并在具有组学护理研究计划或有兴趣开发此类计划的研究人员之间共享样本或数据。常见数据元素(CDE)部分提供了关于将 CDE 纳入护理科学的好处的信息,并链接到美国国立卫生研究院的资源,以促进 CDE 的使用。

结论

ONSEN 为护士科学家和受训人员提供了利用样本和数据集、寻找导师和博士后职位、进一步使用 CDE 以及增强将组学纳入护理科学的教育和技能的机会。

临床相关性

通过 ONSEN 资源推进组学护理科学将加速阐明疾病和相关症状的分子基础,并为制定快速转化、个性化的干预策略提供信息,这些策略基于生物学机制,可改善跨人群和整个生命周期的健康结果。